Zyprexa - antipsychotic medication used in the treatment of schizophrenia and other psychotic disorders.  Zyprexa tablets coated.

Pharmacological action

The active ingredient of the drug Zyprexa has antipsychotic effects. In addition, reviews of Zyprexa reduces suspicion, hostility and aggression alleviates isolation and secrecy, as well as organizes behavior in schizophrenia. In outpatient practice Zyprexa is used to prevent recurrent relapses psychotic state.

Product form

Zyprexa drug release in the form of yellow lyophilizate for solution for intramuscular injection, in vials containing 10 mg of active substance olanzapine.

Zyprexa is also produced in the form of white round tablets with the inscription:

  •   «LILLY 4112", 2, 5 mg;
  •   «LILLY 4115", 5 mg;
  •   «LILLY 4116", 7, 5 mg;
  •   «LILLY 4117", 10 mg.

The blisters of 7 tablets.

If necessary, medication can be replaced by counterparts Zyprexa - Parnasan, Egolanza, olanzapine, olanzapine-Teva, Olaneks, Zalasta in the dosage form of tablets.

Indications Zyprexa

Zyprexa is used according to the instructions:

  • For the treatment of exacerbations of schizophrenia;
  • To carry out long-term and supporting preventive treatment of psychotic disorders with severe negative and positive symptoms, manifested as a reduction in social activity, delirium, automatism, hallucinations, emotional flatness and impoverishment of speech;
  • In the treatment of bipolar disorder as monotherapy or in combination with lithium or valproate;
  • For the treatment of depressive states that are associated with bipolar disorders, often in combination with fluoxetine;
  • To prevent recurrence in bipolar disorder, if Zyprexa was effective in treating manic phase of the disease.


The drug is contraindicated in case of hypersensitivity to the components of Zyprexa. Use Zyprexa as instructed under the age of 18 years, as well as during pregnancy and lactation is not recommended.

Also, caution should be taken when Zyprexa:

  • Epileptic seizures in history;
  • Reduced amounts of leukocytes and neutrophils;
  • Abuse of the bone marrow in history, caused by exposure to medicines or due to concomitant disease, chemotherapy or radiotherapy.

How to use Zyprexa

 Dispersible tablets Zyprexa.
 The recommended starting dose Zyprexa schizophrenia and related psychotic disorders is 10 mg once a day, while the effectiveness of therapy is independent of food intake. Depending on severity of the disease therapeutic dose typically varies in the range of 5-20 mg per day. The recommended starting dose of Zyprexa instructions in bipolar disorder in acute mania is 15-20 mg 1 time a day.

In old age, as well as in renal failure or severe deficiency of liver function usually administered 5 mg per day.

The solution is administered only intramuscularly Zyprexa. The recommended dose of agitation in schizophrenia and bipolar disorder is 10 mg once daily. A second injection at a dose of 10 mg may be administered within two hours, the third - four hours after the second injection.

Dementia manifests as agitation, generally used 2, 5 mg once, repeated injections can be inserted through the first two hours after increasing the dose two-fold.

In old age, as well as instructions for dementia Zyprexa administered in doses of 2 and 5 mg.

To prepare the solution Zyprexa contents of the vial is diluted only with sterile water for injection. Store the prepared solution can be no more than a day.

In applying the drug Zyprexa and analogues should be careful because, like other antipsychotics, it can cause neuroleptic malignant syndrome, which manifests itself as a significant increase in body temperature, sweating, unstable blood pressure or heart rate, muscle rigidity, tachycardia, cardiac arrhythmia, and altered mental status autonomic disorders.

With an overdose of the drug Zyprexa often developed tachycardia, articulation disorder, agitation or aggression, respiratory depression, delirium, hypertension or hypotension, impairment of consciousness of varying severity, heart failure and breathing, convulsions and various extrapyramidal disorder.

side effects

The most common drug Zyprexa Review causes drowsiness, and weight gain and prolactin concentration in the blood plasma.

Besides medication, as well as analogues of Zyprexa, often contributes to the development of dizziness, akathisia, asthenia, peripheral edema, dry mouth, increased appetite, constipation and orthostatic hypotension.

Hyperglycemia, priapism, hypertriglyceridemia, thrombocytopenia and diabetic ketoacidosis Zyprexa Review is in a few cases.

storage conditions

Zyprexa related to prescription drugs with a shelf life of 3 years.