oviraks is an antiviral drug, exhibiting a pronounced activity against herpes simplex, herpes zoster, chickenpox, and less pronounced with respect to the virus cytomegalovirus and Epstein-Barr virus.
The active substance of Zovirax - acyclovir.
This material has the ability to penetrate into the DNA of the virus, causing the occurrence of defective DNA, which can suppress the process of doubling the molecules next generation of viruses.
Thus, the antiviral effect Zovirax is aimed at the disruption of viral replication and the formation of the virus incapable of living units without affecting the healthy cells of the human body.
Zovirax, reviews confirm effective in treating infections of the mucous membranes and skin, caused by the herpes simplex virus, varicella and herpes zoster.
Use Zovirax manual recommends that patients with immunodeficiency and normal immune status for preventing herpes simplex. Zovirax is appointed for the treatment of herpes infections in newborns. The drug is used in bone marrow transplantation for the prevention of cytomegalovirus infection.
Zovirax ointment is indicated for ocular keratitis (inflammation of the cornea) caused by the herpes simplex virus.
Instructions for use Zovirax
For oral administration Zovirax produced in the form of tablets, soluble tablets and capsules.
To prepare the solution for intravenous administration made Zovirax lyophilisate.
For topical acyclovir is produced in the form of lotions and ointments, and ophthalmic ointments.
The time of the drug in tablet form is unaffected by food. Zovirax tablets should drink plenty of water. When herpes simplex administered acyclovir 200 mg every 4 hours (5 times a day). Patients with severe immunodeficiency or intestinal absorption dose of Zovirax manual recommends to double. Duration of treatment - 5 days.
To prevent a recurrence of herpes in patients with normal immune status is assigned a day 800 mg: 200 mg Zovirax every 6 hours or half a dose and increase the interval between doses, respectively. The same scheme Zovirax tablets administered to prevent herpes simplex virus in immunocompromised patients. The drug is continued until, until there is no threat of infection.
Varicella and herpes zoster Zovirax tablets taken within one week of 5 times a day 800 mg.
Children aged two Zovirax the treatment and prophylaxis of herpes administered in the same dose as adults. Children under two years, the dose recommended is halved. Zovirax tablets with shingles and chicken pox the children should be taken within 5 days 4 times a day in the recommended doses: up to 2 years - 200 mg, 2 to 6 years - 400 mg over 6 years - 800 mg.
Zovirax Cream for external topical use. Typically, within 5 days Zovirax cream in a small amount is applied on the affected area, the procedure was repeated up to 5 times per day. If necessary, the duration of the drug may be increased to 10 days.
Eye ointment Zovirax is intended to be placed in the conjunctival sac. Single dose corresponds to a strip of 1 cm. Zovirax ointment applied 5 times a day until symptoms disappear, and then for a further 3 days.
Zovirax intravenously administered guide recommends drip. Typically, Zovirax administered using an infusion pump. For breeding liofilzata use 0, 9% sodium chloride solution. One milliliter of the final solution should correspond to 25 mg of acyclovir. In the treatment of herpes simplex dose calculated by multiplying the weight of 5 mg per patient, herpes encephalitis, herpes zoster, chickenpox in adults and treating herpes simplex neonatal - 10 mg / kg. The resulting dose of Zovirax administered every 8 hours.
The use of oral forms of Zovirax can cause undesirable effects such as:
- abdominal pain, vomiting, nausea, impaired stool, increased activity of liver enzymes, jaundice, acute renal failure;
- confusion, fatigue, hallucinations, dizziness, disorientation, headache;
- anemia, thrombocytopenia, leukopenia, increased creatinine and urea in the blood;
- allergic reactions on the skin, shortness of breath, angioedema, anaphylactoid reactions.
Although Zovirax reviews not informed of possible convulsions and coma, clinical studies suggest that the use of large doses of the drug, such phenomena are possible.
Eye ointment Zovirax can cause angioneurotic edema (swelling of the mucous membranes deep or subcutaneous tissue and skin), burning sensation, blepharitis (inflammation of the eyelid margins), conjunctivitis (inflammation of the mucous membrane of the eye), superficial punctate corneal damage.
Zovirax cream can provoke a manifestation of itching, skin irritation, burning, peeling and dry skin, contact dermatitis. In rare cases may develop angioedema.
Reviews of Zovirax indicate that injection under the skin contact can cause severe inflammatory reactions, including necrosis.
Appoint Zovirax instruction is not recommended in case of hypersensitivity to acyclovir.
Caution is needed when using the drug in neurological disorders, kidney failure, dehydration.
The decision on the advisability of Zovirax pregnant and nursing women should make treating physician.
According to the instructions, Zovirax should be stored at room temperature. Under this condition the drug is fit for 5 years.