Xylene - pharmacological preparation on the basis of vasoconstrictor substances used to treat the common cold.
The active ingredient - xylometazoline.
Structure and Composition
According to the instructions issued in Xylene form of nasal drops.
Besides the active substance, nasal drops also contain auxiliary ingredients: benzalkonium chloride, disodium edetate, sodium hydrogen phosphate dodecahydrate, potassium dihydrogen phosphate, sodium chloride and water.
Xylitol solution is produced in concentrations of 0, 1, and 0%, 05%. The plastic bottle (or a glass) and 10 ml of the drug.
The pharmacological action of xylitol
According to the instructions Xylene has a decongestant action by providing local vasoconstrictor effect. When narrowing of the blood vessels of the nasal mucosa decreases swelling and redness, and restored patency of the nasal passages, which facilitates nasal breathing and relieves nasal congestion. Xylene is beginning to act almost immediately after the application, the effect lasts up to 10 hours.
Since the drug is used topically, it is practically not absorbed into the blood. Modern methods to detect its concentration in the blood after the application fails.
Xylene is used in acute rhinitis caused by viral respiratory infections. The drug is also indicated for acute allergic rhinitis, sinusitis, otitis media when (as part of a treatment to reduce the swelling of the mucous membrane of the nose and throat). Xylene is used prior to rhinoscopy (endoscopic method of examination of the nasal passages and throat).
Contraindications to xylene
This drug is contraindicated in case of hypersensitivity to its components, with advanced atherosclerosis, hypertension, tachycardia, and glaucoma.
Xylene use is contraindicated in patients with atrophic rhinitis, as well as in patients who have a history of surgery, in the meninges. Children under 6 years of age is contraindicated to use 0, 1% solution of this drug, you should use a special children's doses (0, 05% solution).
With extreme caution should be used Xylene in patients with diabetes, prostatic hyperplasia, hyperthyroidism, and coronary heart disease. In the case of contraindications to xylene should not be used alone this drug, talk with the doctor treated the same drugs.
At long (or too often) use of xylitol may be dryness, irritation of nose and throat (which may occur sneezing, burning, hypersecretion of mucus). Occasionally it may be vomiting, headache, palpitations, tachycardia, hypertension, arrhythmia, blurred vision, insomnia, depression. For the occurrence of side effects of xylitol to be a lengthy and in exceeding doses.
Application of xylitol during pregnancy and lactation
Using Xylitol in pregnancy and during breast-feeding is not recommended. By itself, the drug has no adverse effect on the fruit, but it can affect the blood pressure of the pregnant woman, as well as vascular tone placenta.
Dosing and Administration
Xylene should be instilled into each nostril (after pre-purification) 1-2 drops of 0, 1% solution (for adults and children over the years) is not more than 2-3 times per day.
Infants and children up to 6 years recommended the use of 0, 05% xylitol solution 1-2 drops in each nostril once / twice a day.
This preparation should not be used more than three times a day and 5 days.
In case of overdose occur the above symptoms of side effects. Treatment is aimed at ending the use of the drug and the elimination of any symptoms.
Interaction with other drugs
Xylene can not be used simultaneously with MAO inhibitors (monoamine oxidase), and tricyclic antidepressants.
Specific guidance on the use of xylitol
Before instillation of the drug in the nasal passages should clear them. In chronic rhinitis unacceptably prolonged use of xylitol.
This drug is in the recommended dosages do not affect the ability to drive vehicles and work requiring high concentration.