Xenical - inhibitor of gastrointestinal lipases, used to treat obesity in various stages.

Pharmacological action

Active substance Xenical blocks absorption of fat from the small intestine, whereby the uncleaved fats excreted.

This reduces the amount of calories consumed and, consequently, weight. Since the therapeutic effect is carried in the intestines, the drug is not absorbed into the bloodstream, it can be used for a long time.

Preparation action begins 1-2 days after ingestion. Note, however, that the abolition of Xenical fat content returns to the previous level.

Product form

Xenical manufactured as turquoise opaque hard gelatin capsules containing white pellets. Each capsule contains 120 mg of active substance - orlistat. 21 piece per blister.

Indications Xenical

According to the instructions Xenical is used for long-term therapy in overweight and obesity, combining treatment with a reduced-calorie diet.

Also pill Xenical is used in combination therapy with hypoglycemic agents (sulfonylureas, metformin, or insulin) in the treatment of overweight and obesity in diabetes mellitus type 2.


Instructions for Xenical is contraindicated in:

  • Hypersensitivity to the drug;
  • Cholestasis;
  • Chronic malabsorption syndrome.

Instructions for use Xenical

 Xenical tablets

According to the instructions Xenical used three times a day, during each main meal, one capsule.

The drug can be skipped when taking low-fat food. It should be noted that the use of higher doses does not increase the slimming effect of Xenical.

The drug can be taken with abnormal liver function, as well as the elderly unchanged dosage. Children under 18 years of Xenical for weight loss is not recommended due to lack of research.

Side effects

In the opinion of Xenical is often side effects of the gastrointestinal tract that is caused by the pharmacological action of the drug.

Very often there are side effects from the digestive system -

gassing with an amount of discharge, oily discharge from the rectum, steatorrhea, fecal urgency, loose stools, more frequent bowel movements, discomfort or pain in the abdomen, bloating.

The incidence of these effects, in the opinion of the Ksenikale depends on the fat content of the food you eat.

Typically, these side effects occur during the first three months of treatment.

Also, when using Xenical for weight loss can be observed:

  • Rash;
  • Pancreatitis;
  • Headache;
  • Anxiety;
  • Infections of the upper and lower respiratory tract;
  • Urinary tract infections;
  • Angioedema;
  • Anaphylactic reactions;
  • The defeat of the teeth and gums;
  • Hives;
  • Dysmenorrhea;
  • Weakness;
  • Rectal bleeding;
  • Diverticulitis;
  • Cholelithiasis;
  • Itching;
  • Bronchospasm.

Xenical reviews of the most effective for long-term use, reducing risk factors for diseases that accompany obesity (impaired glucose tolerance, type 2 diabetes, hypertension).

With simultaneous use of Xenical tablets with vitamins A, E, K, and D decreases the absorption of these vitamins. The concentration of these vitamins in the use of the drug remains in the normal range. Also during the pills Xenical can be used multivitamins, which should be applied after taking the drug no earlier than 2 hours.

Simultaneous treatment with Xenical and acarbose is not recommended due to the lack of pharmacokinetic studies.

Also, no studies use Xenical during pregnancy and lactation, therefore use in patients in these periods is not recommended.

Storage conditions

Xenical is related to drugs List B and prescription. Shelf life - 3 years.