VFS - a drug for the treatment of diseases of the cardiovascular system.

Release form and composition

VFS manufactured in the form of tablets and solution.

The structure of the round, biconvex white tablets includes:

  • Lappaconitine hydrobromide (VFS) - 25 mg;
  • Sucrose (sugar, refined sugar or sugar) - 65 5 mg;
  • Potato starch - 7, 5 mg;
  • Calcium stearate (calcium stearate) - 1 mg;
  • Croscarmellose Sodium - 1 mg.

Solution for intravenous or intramuscular injection comprising 2 ml of 5 mg / ml of active ingredient.


According to the instructions, VFS is used for heart rhythm disturbances:

  • Ventricular and supraventricular arrhythmia;
  • Paroxysms of atrial fibrillation and atrial flutter;
  • Ventricular and supraventricular paroxysmal tachycardia.


Applications VFS is contraindicated in:

  • Cardiogenic shock;
  • Severe hypotension;
  • Renal or hepatic impairment;
  • Intraventricular conduction blockade;
  • Chronic heart failure degree II-III;
  • Right bundle branch block;
  • Pregnancy;
  • Lactation.

Under medical supervision taking the drug, children and adolescents up to 18 years, and patients with:

  • To compensate for chronic heart failure;
  • Bradycardia;
  • Angle-closure glaucoma;
  • Prostatic hypertrophy;
  • Blockade AV I degree;
  • Conduction disorders of Purkinje fibers;
  • Electrolyte imbalance;
  • The blockade of one of the legs-branch block;
  • Cardiomegaly.

Caution is required when pacing.

During treatment it is necessary to take into account that the use of VFS enhances the action of non-depolarizing muscle relaxants.

Efficiency Allapinin reduce inducers of microsomal liver enzymes, anti-arrhythmia other classes. The combination with inhibitors of microsomal oxidation can cause toxic complications.

Dosage and Administration

VFS according to the instructions take every 8 hours to 0, 025 g

If there is no effect, the daily dose can be increased by increasing the multiplicity of reception - every 6 hours. Acceptable unit dosage increasing to 0, 05 g, are administered every 6-8 hours.

The course of treatment may last several months. In general, the duration depends on the degree of cardiac arrhythmias, and general condition of the patient.

The maximum allowable dose: daily - 0, 3 g, single - 0, '05

The action of the drug in the internal application starts after 40-60 minutes after taking the tablets and lasts for more than 8 hours.

For intramuscular and intravenous use Allapinin dilute sodium chloride solution and administered intramuscularly every 6 hours at 0 dose of 4 mg / kg and intravenously - 0 3-0 4 mg / kg, for 5 minutes.

After 6 hours, if necessary, can enter the second dose - 0, 3 mg / kg.

When administered intravenously, the therapeutic action begins in 15-20 minutes and persists for 6-8 hours.

Side effects

VFS can cause headache, ataxia, dizziness, diplopia, sinus tachycardia, intraventricular conduction slowing, redness of skin, allergic reactions.


When side effects, reduce the dose.


Analogues Allapinin of the active substance there. Close mechanism of action has Etmozin.

Terms and conditions of storage

Store at temperatures not above 25 ° C. Keep away from children. Shelf life - 5 years.