Velafaks 75 mg
 Velafaks - antidepressant agent

Pharmacological action

Action Velafaksa based on its ability to stimulate the transmission of impulses in the nervous central system.

The active ingredient of the drug - venaflaksin, the chemical composition is not related to any of the known groups of anti-depressant medications.

Product form

Velafaks release tablets.


Velafaks administered to prevent, treat depression.

This positive feedback on Velafakse say that lend themselves to any drug treatment of depression, regardless of the reason they were called.

Instructions Velafaksa: how to use

Take Velafaks recommend eating.

Begin 37 therapy dosages, 5 mg, that accept two rows daily / day. After a few weeks of monitoring the state of the patient, and if there is no improvement, increase the daily dose of 150mg, which take in two steps.

If there is severe depression, or the patient requires supervision in a hospital, an increased dosage prescribed to take the first days of therapy and gradually increase it (every two or three days) for a further 75mg, until it is expected therapeutic effect. This takes into account that more than 375mg per day of the drug can not be taken.

After steady improvement occurs, the dose begins to decrease, selecting the optimum. There are reviews of Velafakse indicating that for the prevention of failure and to secure the resulting effect of the treatment should be continued for another six months.

For patients suffering from renal insufficiency, mild, a change in the standard mode Velafaksa purpose is required. For patients with moderate renal insufficiency severity, reduce dosage by 25-50%, and recommend taking a daily dose at a time.

When liver failure mild dosage Velafaksa not corrected, at insufficiency of moderate severity is reduced by 50%.

For elderly depressed patients do not need to adjust the dosage, but treatment is initiated with a minimum effective dose gradually, if necessary, by increasing it - to avoid kidney damage. If necessary, use of high doses of Velafaksa, patients were followed and treated in a hospital.

The instructions Velafaksa also pointed out that treatment should be stopped gradually, at least for a week, watching the condition of the patient.

Patients who are on dialysis is usually reduced by half the standard prescribed daily dosage of the drug, and only after the end of hemodialysis.

side effects

Velafaks can cause constipation, vomiting, hepatitis, poor appetite, dry mouth, an increase in the amount of cholesterol, reduced weight, increased pressure, flushing, tachycardia, decrease in pressure (rare).

There are reviews of Velafakse, causing urinary retention, difficulty urinating, erectile dysfunction and ejaculation, impairment of libido, menorrhagia, anorgasmia.

May occur during treatment with mydriasis, blurred vision, accommodation, taste, can be broken photosensitivity, erythema multiforme occur, develop Stevens-Johnson syndrome.

In some cases, due Velafaksa appear hemorrhages on the skin and mucous membranes, thrombocytopenia, rash, anaphylactic reaction develops.

In addition, patients taking Velafaks, marked weakness and fatigue.

Abrupt withdrawal syndrome Velafaksa expressed in increased sleepiness, nausea, anorexia, headache, vomiting, dry mouth, diarrhea, anxiety, irritability, dizziness, disorientation, paresthesia, sweating, hypomania.  Tablets Velafaks 37 5 mg

Contraindications Velafaksa

Velafaks is contraindicated in severe renal, liver failure is suspected and during pregnancy, during lactation, in case of hypersensitivity.

Do not give medication to children under 18L.

Be wary of Velafaks instructions given to patients who have had a heart attack, suffering from unstable angina, tachyarrhythmia, hypertension, tachycardia, increased intraocular pressure, glaucoma closure, a tendency to bleeding, and patients with low weight and suffered in the past manic states, convulsive syndrome.

You can not assign Velafaks concurrently with MAO inhibitors. The drug affects the blood concentration of clozapine, which increases the risk of side effects.

Velaflaks enhances the effects of alcohol on psychomotor reactions. Also note that the drug enhances the effect of haloperidol.

There were no significant interactions Velafaksa with drugs that lower blood pressure and blood sugar, with diazepam.