Tsipraleks - a preparation from the group of antidepressants, the mechanism of which consists in the selective inhibition of serotonin reuptake.  Tsipraleks per pack
 This leads to an increase in the content of this neurotransmitter in the synaptic cleft substance, enhancing and prolonging its effect on the area of ​​the postsynaptic receptor sites. The composition includes the active ingredient Tsipraleksa - escitalopram, which has a very high selectivity, i.e. virtually not bind to other receptors, including serotonin 5-NT1A- 5-NT2-, dopamine, adrenergic, histamine H1-M-cholinergic receptors. benzodiazepine and opioid receptors. Due to these properties, the treatment of depressive syndromes Tsipraleksom very effective. The drug is widely used in the mental practice and the positive feedback on Tsipralekse talk about the high activity of the drug.

Product form

Preparation Tsipraleks as coated tablets containing 5, 10, 20mg active ingredient.

Indications for use of the drug Tsipraleks

According to the instructions, Tsipraleks apply under the following conditions:

  • depressive episodes regardless of severity;
  • panic disorder with or without agoraphobia.

Contraindications Tsipraleks

The instructions to Tsipraleksu contain the following contraindications to the use of this drug:

  • Hypersensitivity to the active substance and the auxiliary components included in the composition of the drug;
  • simultaneous intake of the group of MAO inhibitors;
  • pregnancy;
  • lactation;
  • age up to 15 years.

Use during pregnancy and lactation

Treatment Tsipraleksom during pregnancy and lactation is contraindicated. In the application of selective serotonin reuptake inhibitors during pregnancy were observed in newborns psychophysical symptoms suggestive of serotonergic effect, as well as the occurrence of withdrawal syndrome. Therefore, in the case of using Tsipraleksa or analogues during pregnancy their use should not be interrupted rapidly.

Side effects

When applied according to the instructions Tsipraleksa side effects are rare, usually in the first week of therapy, and then their intensity is greatly reduced. You may experience the following side effects:

  • From the digestive system may cause nausea, diarrhea, loss of appetite, constipation, vomiting, dry mouth, loss of functionality of the liver;
  • From the nervous system: dizziness, insomnia or drowsiness, visual disturbances, tremors, seizures, disorders of motor activity, taste, hallucinations, confusion, mania, serotonin syndrome, agitation, depersonalization, anxiety, panic attacks;
  • on the part of the reproductive system: men may reduce libido, ejaculation disorder, impotence, women - anorgasmia;
  • from the vascular system may develop orthostatic hypotension;
  • on the part of the endocrine system: galactorrhoea, inadequate secretion of ADH;
  • Other side effects may develop anaphylactic reaction, skin rash, pruritus, purpura, ecchymosis, arthralgia, myalgia, urinary retention.

These phenomena are often the cause of the negative reviews Tsipralekse by the patients, but with proper use of the drug side effects quite quickly cease.  Tablets Tsipraleks

Treatment Tsipraleksom need to stop smoothly as possible the development of the syndrome include nausea, dizziness, headache.


Overdose symptoms are dizziness Tsipraleksa, agitation, tremor, sleepiness, impaired consciousness, seizures, ECG changes (changes in the T wave, the segment ST, the expansion of QRS, lengthening of QT), arrhythmia, respiratory distress, vomiting, metabolic acidosis, rhabdomyolysis, hypokalemia.

In overdose Tsipraleksom symptomatic and supportive therapy, as there is no specific antidote. Conducted intensive gastric lavage, needs an adequate oxygen supply, monitoring the activities of the respiratory and cardiovascular systems.

Method of use and dosage of the drug Tsipraleks

According to the instructions, Tsipraleks administered orally, regardless of food intake, the daily dose - in one step.

If depressive episodes therapeutic dose is 10, a maximum of 20mg per day.

Antidepressant effect Tsipraleksa develops after 2-4 weeks of treatment. After a therapeutic effect Tsipraleksom treatment should continue for at least 6 months.

When panic disorders recommend the following regimen Tsipraleksa and analogues: the dosage of the first week of treatment - 5 mg, then increased to 10 mg. The maximum daily dosage Tsipraleksa - 20mg.

The therapeutic effect in this pathology develops within 3 months. Treatment Tsipraleksom in this situation should also take several months.

The recommended daily dosage Tsipraleksa for elderly patients half.

Patients with kidney and liver (mild to moderate), dosage adjustment is not necessary. However, with a decrease in creatinine clearance less than 30 ml / min to apply Tsipraleks and analogues should be with caution.

In order to prevent the development of withdrawal Tsipraleksa need to reduce the dosage gradually, within two weeks.

Interaction with other drugs Tsipraleksa

When using Tsipraleksa and MAO inhibitors significantly increases the risk of serotonin syndrome. It's possible complication while taking serotonergic drugs. Possible increased risk of seizures while applying Tsipraleksa and drugs that reduce the seizure threshold. Tsipraleks enhances the effect of medicines that reduce blood clotting, so, while the appointment of these drugs requires constant monitoring of hemogram. Tsipraleks increases blood levels of drugs such as desipramine, and metoprolol.

Reviews Tsipralekse

Due to the high efficiency of reviews of Tsipralekse good enough. The drug significantly reduces the symptoms of neuropsychiatric disorders with depressive syndrome. However, the drug has many side effects, so it is necessary to study carefully the instructions in the Tsipraleksu before using this drug.

Analogs Tsipraleksa

Currently, there are pharmacies following analogues Tsipraleksa: Lenuksin, Miratsitol, Santsipam, selectors, Elitseya, Escitalopram, Teva.

storage conditions

The drug belongs to the list Tsipraleks B. Tsipraleks should be stored at room temperature out of reach of children. Sold by prescription only.

Use this drug can only be prescribed by a doctor for.