Tizin - a synthetic drug for topical application in the treatment of certain eye diseases, as well as to reduce the swelling of the mucous membranes of the nose caused by allergies or infectious diseases.

Pharmacological action tizin

 Active ingredient tizin acting alpha-agonists, with the local application has decongestant and vasoconstrictive action. Thus vasoconstrictor effect develops quickly enough for a few minutes. The drug remains in effect up to eight hours.

In the systemic application of the instructions provided Tizin central sedative effect, which allows not to use the drug further night.

Product form

Tizin produced in the form 0, 1% nasal drops (0, 05% - for children) in bottles of 10 ml.

Analogs tizin

Tizin analogues of the active substance are the following drugs: Visine, VizOptik, octyl and Montevizin.

Furthermore, in some cases, after consultation with the doctor is allowed to use analogues tizin mode of action. These medications include eye drops Betadrin, Okumetil, Polinadim, spersallerg, Oftofenazol, Ditadrin and Sanorin-Analergin.

Indications tizin

According to the instructions Tizin prescribed for the treatment of:

  • Secondary congestion on the background of allergic diseases of the eye;
  • Swelling of the conjunctiva;
  • Catarrhal conjunctivitis;
  • Conjunctival irritation.

Furthermore, the use of reviews tizin effective in edema of the nasal mucosa in the background:

  • Sore throat;
  • Rhinitis;
  • Hay fever;
  • Sinusitis.

Drops Tizin also appointed prior to the therapeutic and diagnostic measures (to reduce swelling of the nasal mucosa).


Tizin for instructions apply contraindicated in case of hypersensitivity to the active or auxiliary components drops.

In pediatrics for the drug, the following contraindications:

  • 0 05% solution (for intranasal use, and in the case of treatment of glaucoma and endothelial corneal epithelial dystrophy) - 2 years;
  • 0, 1% solution - 6 years.

We recommend using Tizin with caution during treatment with MAO inhibitors and other drugs that contribute to high blood pressure during pregnancy and lactation, as well as on the background:

  • Hypertension;
  • Thyrotoxicosis;
  • Arrhythmias;
  • Diabetes;
  • Pheochromocytoma.

Dosing tizin

Drops Tizin recommended instilled two-three times a day in each conjunctival sac. Generally, treatment is terminated if there is no improvement in two days.

Intranasal Tizin instructions on how to assign children (over 6 years) and adults 2-4 drops. For children of 2-6 years use 0, 05% solution in a single dose of 2-3 drops of not more than four times per day (every 3-4 hours).

The duration of continuous use tizin not exceed four days.  Tizin children

Side effects tizin

When using tizin to treat eye diseases can develop:

  • Mydriasis;
  • Reactive hyperemia;
  • Increased intraocular pressure;
  • Burning sensation in the eyes.

When using the drug as a means to nose Tizin Review can cause:

  • Tingling or burning sensation in the nose;
  • Dryness of the nasal mucosa;
  • Sneezing.

With prolonged use of Tizin reviews can lead to secondary swelling of the nasal mucosa.

Furthermore, the active ingredient tizin Review cause systemic effects that often appear in the form:

  • Nausea;
  • Headache;
  • Weakness;
  • Drowsiness;
  • Dizziness;
  • Tremor;
  • Palpitations;
  • Insomnia;
  • Hyperglycemia;
  • Tachycardia;
  • Disorders of the heart;
  • Increased blood pressure;
  • Allergic reactions.

Prolonged use tizin and excess of therapeutic doses, in some cases leading to overdose, which usually manifests itself as:

  • Cyanosis;
  • Mydriasis;
  • Cardiac arrest;
  • Convulsions;
  • Fever;
  • Increased blood pressure;
  • Arrhythmias;
  • Dyspnea;
  • pulmonary edema;
  • Central nervous system depression, which is accompanied by lethargy, hypothermia, apnea, collapse, coma, and bradycardia.

The risk of these symptoms caused by the absorption of the drug, is highest in young children and occurs most often by ingestion of the drug solution.

For the treatment prescribed, generally, gastric lavage, oxygen inhalation, activated carbon, and drugs that reduce blood pressure, body temperature, and antiepileptics.

Drug Interactions

Tizin of instructions can not be used simultaneously with MAO inhibitors.

Storage conditions tizin

Drops Tizin dispensed by prescription. The shelf life of the drug - 5 years, open a bottle tizin should not be used longer than a month since it opened.