Tiapride - oriented with antipsychotic drug for the treatment of diseases of the nervous system.

Pharmacological action

Tiaprid by its very nature is an atypical antipsychotic.  Tiaprid 30 tablets
 He has antipsychotic, analgesic, sedative, anxiolytic and hypnotic effect. Its mechanism of action is to block receptors of various brain structures. It is able to selectively bind to the dopamine type 2 receptors in mesolimbic and Mesocortical zones, essentially no effect on type 1 receptors, thereby realized neuroleptic action. Acting on the same receptors in the hypothalamus (in the center of thermoregulation) tiaprid has hypothermic effect, emetic center - an antiemetic effect. Sedative effect due to adrenergic blocking in the reticular formation of the brain.

Tiaprid well eliminates somatic and visceral pain. It inhibits productive symptoms, eliminating the central dyskinesia increases the effects of other antipsychotic drugs, lowers the threshold of epileptic activity in patients with epilepsy and improve cognitive abilities in the elderly.

The drug almost immediately enters the bloodstream when taken orally, with simultaneous reception of food affects the absorption tiaprid. He is well passes through the blood-brain barrier. Because the body tiaprid excreted unchanged by the kidneys.

Product form

Tiapride by instructions available in tablets of 100 mg and a solution for intramuscular or intravenous administration in vials of 2 ml (50 mg / ml).

Indications tiaprid

The drug is used for treatment of hyperkinesia and dyskinesia, including Parkinsonism. Apply it with a nervous tic, tremor, in the case of acute and chronic chorea, with behavioral disorders in old age, with psychomotor agitation and alcoholism.

In the opinion of tiaprid well it eliminates the pain in the case of chronic pain, cancer patients, pain neurogenic origin, headache. It is able to eliminate behavioral disorders with aggression and agitation.


Tiaprid can not be used if patients prolaktinzavisimyh tumors, pheochromocytoma, in case of hypersensitivity to the drug during pregnancy and lactation, children under 7 years old. With care it is used in the case of epilepsy, decompensated heart disease, chronic renal failure. At the time of treatment should refrain from work that requires concentration.

Instructions for use tiaprid

Tiapride taken orally in the minimum effective dose to start with a low dose. The average adult humans it is 2 - 4 tablets per day.

In case of movement disorders, the dose is 1 - 2 tablets three times a day, in psychomotor excitation maximum tolerated dose of 12 tablets per day.

For headaches, alcoholism begin with 200 - 400 mg / day, gradually reducing the dose to 100 - 200 mg / day.

Chorea tiaprid for instructions since taking 25 mg / day, gradually bringing it up to 300 - 800 mg / day.

Children dosage calculated on the weight of the body, and since 7 years of 3 - 6 mg / kg / day.  Tiaprid 20 tablets

For intravenous and intramuscular injection in the case of severe pain enough 200 - 400 mg / day, children from 7 years old - 100 - 150 mg / day. The duration of treatment is individual, it determines the physician depending on the dynamics of symptoms.

Side effects tiaprid

In the opinion of tiaprid can cause drowsiness, dizziness, headache, menstrual disorders, breast enlargement, galactorrhea.