Sumamed antibiotic belongs to the group of macrolides.

Pharmacological action Sumamed

Sumamed has a bacteriostatic effect and in high concentrations (4 - 8 times the minimum inhibitory concentration) is also bactericidal. The main active ingredient of it - azithromycin. On this basis there are analogues Sumamed as Azitroks, Zitrolid, Zimaks, Hemomitsin and others.  Sumamed capsules (500 mg)

The mechanism of action of the drug is that it gives the biosynthesis of protein in the microbial cell by binding to its ribosomes. The bacteria are broken metabolism and growth, reproduction is blocked, whereby it dies.

Sumamed instructions for a broad spectrum of antimicrobial activity. He is able to act detrimental to many species of bacteria - gram (different types of streptococci and staphylococci), Gram-negative (Haemophilus influenzae, pertussis, gonococcus, meningococcus, gardnerelly, morakselly, Helicobacter), anaerobes (Clostridia, and peptokokki peptostreptokokki).

The great advantage compared to other antibiotics is the property as a macrolide Sumamed penetrate cell membranes and effectively act on intracellular microorganisms (so-called atypical bacteria), such as chlamydia, mycoplasma, ureaplasma, legionella.

We know about the anti-inflammatory effect of the antibiotic Sumamed not associated with antibacterial activity directly. This effect is due to the antioxidant capacity - effects on cyclooxygenase and the formation of superoxide ions of oxygen. One of the anti-inflammatory effects is to reduce the formation of mucus in the bronchi due to suppression of tumor necrosis factor, this property is particularly valuable in the treatment of respiratory infections in patients with cystic fibrosis. Application of Sumamed in the complex therapy in these patients improves airway. This is possible because of a violation of Education alginate, which harbors a colony of Pseudomonas aeruginosa (it is almost always present on the mucous membranes in cystic fibrosis) from the action of antibiotics.

Analogs Sumamed as he possess specific immunomodulatory properties by exposing the white blood cells - leukocytes. Sumamed stimulates the immune system to fight infection and inflammation, and in addition, to the extent subsided the infectious process stops have unwanted immune attack. Like other peers Sumamed he postantibiotic peculiar effect. Its meaning is that after a minimum duration of contact with the drug in the ribosomes microbe irreversible changes occur, resulting in protein synthesis is blocked and bacteria are killed. Thanks to this antibacterial Sumamed extended and enhanced. This is most clearly evident in regard to Haemophilus influenzae and Streptococcus group A

Sumamed Review less than other antibiotics, affects the normal intestinal flora by ingestion. It rarely causes goiter. Diarrhea, which is against the background of his admission, due to increasing bowel contractions and accelerate progress of its contents (the so-called motiliumopodobny effect).

When using Sumamed inside it is well absorbed and distributed to body tissues, reaching high concentrations in them and derived from them slowly. Due to this possible reception Sumamed under the instruction once a day, and a short course - only 3 days. The source of infection drug concentration is one third more than in healthy tissues as leukocytes capable aktivnoperenosit it into the lesion. In the liver, the drug is metabolized and excreted in the bile into the intestinal lumen and very little - in the urine.

Product form

Sumamed produced in the form of capsules, 250 mg; tablets, coated tablets, 125 mg and 500 mg; powder for suspension inwardly 100mg / 5 ml in a vial and 20 ml Sumamed forte as a powder for suspension 200 mg / 5 ml in 20 ml vials and 30 ml. It is also possible to use Sumamed in injectable form for intravenous infusion, it is produced in the form of a powder in vials of 500 mg.

Indications Sumamed

Sumamed antibiotic used in the treatment of infections caused by susceptible to the microorganism. The list of such diseases are infections of of upper respiratory tract (sinusitis, tonsillitis, pharyngitis), respiratory system (bronchitis, pneumonia), urinary tract (urethritis, cervicitis), skin and soft tissues, joints, in the initial stage of borreliosis. Sumamed got good reviews in pediatric practice.


The drug is not recommended to use it in case of intolerance and other macrolides with severe kidney and liver, while the use of ergot drugs during lactation. Reviews of sumamed during pregnancy is not, in this case the benefits should be greater than the perceived risk to the fetus.

Instructions for use Sumamed

Forms of preparation for oral administration taken 1 time a day 1 hour before meals or 2 hours after it with water. Especially for children from 6 months Sumamed antibiotic is produced in powder form for preparation of the suspension at a dosage of 100 mg / 5 mL and 200 mg / 5 mL, and 3 years - tablets of 125 mg.  Form release Sumamed
 The dose is calculated on the weight of the child - 10 mg / kg / day, a course of treatment lasts 3 days. In chronic erythema migrans regimen is a little different - on day 1 at the rate of 20 mg / kg / day, with a 2 to 5 day - 10 mg / kg / day. To prepare a suspension, the vial was added 11 mL of water. Due to the fact that during the extraction the suspension from the vial it possible losses, the actual volume (25 ml) is slightly larger than the nominal (20 mL). The finished suspension Sumamed store in the refrigerator no longer than 5 days prior to use it is necessary to shake.

Adults and children over 12 years is more convenient to take capsules of 250 mg and 500 mg tablets. They were swallowed without chewing. Average dose - 500 mg 1 time a day, the course of 3 days. At day 1 borreliosis 1d, from 2 to 5 days on 500 mg 1 time per day. In uncomplicated urethritis or cervicitis chlamydial origin take 1 g once Sumamed.

Side effects

In the opinion of Sumamed well tolerated during the treatment. Occasionally can be against treatment such undesirable phenomena such as allergic dermatitis, headaches and dizziness, nausea, abdominal pain and diarrhea, joint pain, changes in general and biochemical analysis of blood, weakness, fungal infections of the mouth and genitals.