Meronem - an antimicrobial agent.

Pharmacological action

The active ingredient of the antibiotic Meronem - meropenem with bactericidal effect of the carbapenem group.

Meronem is active against corynebacteria, lactobacilli, enterococci, streptococci, bacillus, staphylococcus, aeromonov, enterobacteria Escherichia coli and Haemophilus influenzae, atsinobakterov, Brucella, gardnerelly, campylobacter, Klebsiella, Neisser, Helicobacter pylori, Proteus, moraksell, shigella, vibrio cholerae, yersenii, Salmonella, Pseudomonas, fuzobakterii, actinomycetes, bifidobacteria, Bacteroides, Clostridium.

Meronem throughout all tissues, biological fluids, including cerebrospinal fluid, which makes it possible to use the drug for the treatment of meningitis.

Product form

The antibiotic Meronem produce powder for solution infusion.

Indications Meronema

Meronem by instructions prescribed for: pneumonia, inflammations of the urogenital system, soft tissue and skin of the abdomen, at a temperature of febrile patients with low immune status (therapy Meronem in this case may be combined with antiviral, antifungal agents).

Effective drug for the treatment of meningitis, sepsis, superinfection.


Meronem is contraindicated in children under the instruction up to three months, in case of hypersensitivity

During pregnancy, the drug is prescribed in special cases, on strict conditions. When breastfeeding is not recommended to use an antibiotic.

It is undesirable to take Meronem concurrently with nephrotoxic drugs, also known that antibiotics can reduce the level of valproic acid.

Preparation probenecid while appointing with Meronem may increase its concentration.

Meronem is undesirable given to patients with intolerance carbapenem, penicillin, because it may be cross-allergy.

With care prescribe to patients with pathology of the gastrointestinal tract - due to risk of pseudomembranous colitis.

The rate of psychomotor reactions drug action is not.

Instructions for use Meronema

Meronem at genitourinary, skin infections, pneumonia is used as an intravenous infusion - 0, 5g three p / day over the same period.

For the treatment of nosocomial pneumonia, peritonitis, sepsis, presumably infection in patients with immune status understated Meronem 1g administered three p / day and at regular time intervals.

Meronem cystic fibrosis, meningitis administered at 2g three p / day c / o same time intervals.

Patients with renal disease who are on hemodialysis, an extra dose of the drug is obtained after the treatment in patients with renal failure is a dosage adjustment. Patients with liver failure, elderly patients do not need to adjust the dose.

 The antibiotic Meronem
 For children the dosage according to the instructions Meronem calculated based on their weight. Children under the age of 3-month-12L. antibiotic is administered in a volume of 30-60mg / k, the daily dose should be divided into three stages. Children weighing more than 50kg, regardless of age, to take prescribed antibiotic Meronem in "adult" doses.

In some cases, children are given higher doses. For the treatment of meningitis prescribe 120mg / kg, chronic respiratory diseases, cystic fibrosis - 75-120mg / kg.

Meronem administered either by infusion over half an hour, or by bolus injections over five minutes. To prepare the solution for bolus injections Meronem bred a special water: 250 mg of the antibiotic to 5 ml of water.

For intravenous drip to add Meronem 50-200ml fiz.rastvora glucose solution or 5, 10%.

side effects

Meronem rarely causes adverse effects, in some cases, there are headaches, nausea, leukopenia, seizures, anemia, candida, indigestion, changes in the level of liver samples, allergic anaphylaxis, pruritus, rash, angioneurotic edema.

Overdose causes symptoms similar to the side effects. In this case shown hemodialysis.