Teraflex - agent for the treatment of degenerative diseases of the musculoskeletal system.
Pharmacological action Teraflex
The structure includes two terafleks active ingredient - chondroitin sulphate and glucosamine.
Both enhance regeneration (recovery) of the cartilage of the articular surfaces of degenerative lesions.
Glucosamine is involved in the formation of glycosaminoglycans (including hyaluronic acid) which form the basis of cartilage. Acting as antioxidants, it protects cartilage from destruction by oxygen radicals, which are formed during inflammation. Also glucosamine protects the cartilage articular surfaces from the damaging effects of metabolic products using non-steroidal anti-inflammatory drugs and glucocorticoids. There is information about its anti-inflammatory effect of a moderate.
Chondroitin sulfate belongs structurally to the group of the mucopolysaccharides. It reduces the activity of cartilage-destroying enzymes. Stimulating the formation of proteoglycans, collagen and gialuronona, it also restores the structure of cartilage and support the necessary viscosity of the synovial fluid. Glucosamine and chondroitin sulfate complex potentiate each other's effect.
Application Teraflex slows the degeneration of joint cartilage and improves the metabolism in the cartilage. This reduces joint pain and stiffness in their motion. In the opinion of Teraflex to reduce the dosage of NSAIDs and analgesics.
The drug is absorbed from the digestive tract and reaches its maximum concentration in serum after 4 hours, and in synovial fluid after 4 - 5 hours. About one-third of its concentration fall in the joint fluid and cartilage. The low bioavailability is related to the large size of the molecules of glucosamine and chondroitin sulfate.
The drug is metabolized in the liver to produce safe products of metabolism, and for one day removed from the body by the kidneys.
There are several unique Teraflex, they include additional components that enhance the therapeutic effect. For example, in Advance terafleks composition contains also NSAIDs ibuprofen and Teraflex M in the form of ointment contains camphor and mint oil.
According to the instructions Teraflex release capsules.
The drug is used in treatment of diseases of bones and joints in the presence of degenerative changes in the cartilage. These include - osteoarthritis, osteoporosis, spondylosis, osteochondrosis and other degenerative dystrophic diseases of the spine. Good reviews Teraflex got in the practice of post-traumatic states - it accelerates callus formation and, consequently, a fusion of bones in fractures.
According to the instructions Teraflex contraindicated in case of intolerance to its components, phenylketonuria, children under 15 years. Reviews Teraflex during pregnancy and lactation are not available, so the drug for these conditions is not recommended.
Precautions can be applied at an elevated bleeding, diabetes, chronic renal failure.
Instructions for use Teraflex
The drug is taken orally, drinking water, regardless of meals. During the first 3 weeks recommend 1 capsule three times a day, then continue taking 1 capsule 2 times a day during 3 - 6 months. The duration of the course, depending on the stage of the disease determined by a physician. After a break of one month course, if necessary, repeat.
It is important to remember that, like its counterparts, Teraflex enhances the effect of anticoagulants. It also reduces the activity of penicillin antibiotics.
Typically, the use of Teraflex safely and does not disturb the well-being of patients. Rarely are abdominal pain, diarrhea, constipation, headache, drowsiness, insomnia, or allergic reactions.