Teofedrin - combined drug, providing a bronchodilator and antispasmodic effect. Analogues Teofedrin considered Bronhofilin T-Fedrin and Trifedrin IP.
Release form and composition Teofedrin
The composition teofedrina predominate anhydrous theophylline (0, 1 g), phenobarbital (20 mg), ephedrine hydrochloride (20 mg), anhydrous caffeine (50 mg), paracetamol (0, 2 mg), belladonna extract thick (3 mg) cytisine (0, 1 mg).
In addition to the main operating components of the Teofedrin include microcrystalline cellulose, potato starch, croscarmellose sodium, calcium stearate, aerosil, plasdon S-630, talc.
Pharmacological action Teofedrin
Teofedrin and analogues Teofedrin relax the smooth muscles of the bronchi. The action of the tool increases the bronchial lumen, dilates blood vessels of the lungs, increases the frequency and strength of heart contractions, increase heart blood flow. The drug is an anti-inflammatory effect, has M-anticholinergic activity and moderate diuretic effect. Caffeine is a part Teofedrin eliminates the feeling of fatigue and drowsiness, stimulates the psychomotor centers of the brain, increases the effects of analgesics, has analeptic effect.
Non-narcotic analgesics acetaminophen in the composition of the drug blocks the COX in the central nervous system and acts on the thermoregulatory centers and pain. Phenobarbital has a muscle relaxant and antispasmodic action. Phenobarbital composed Teofedrin provides long and mild sedative effect, and adjusts the psycho-emotional state of a patient with broncho-obstructive syndrome of different origin.
Ephedrine hydrochloride stimulates the adrenergic receptors of the bronchi, causing their expansion and increasing the excitability of the respiratory center. Respiratory analeptic cytisine reflexively stimulates the respiratory center enhance the momentum that comes from the carotid glomeruli.
Belladonna extract contains alkaloids atropine group, has analgesic and antispasmodic effect.
The instructions to Teofedrin indicated that the drug can be used for the treatment of asthma or obstructive bronchitis in the chronic form. Use of the drug is appropriate and emphysema.
Teofedrin - Instructions for use
According to the instructions Teofedrin adult patients should be taken orally at 0, 5-1 tablet once a day. If necessary, the daily dose can be increased three times. It is also permissible increase teofedrina single dose (two tablets of the preparation up to three times a day). Children from two to five years is prescribed for 0, 25-0, 5 tablets, for children from six to twelve years - at 0, 5-0, 75 tablets. Teofedrin should be taken in the morning or in the afternoon. The duration of treatment should be to establish a doctor.
Teofedrin and analogues Teofedrin contraindicated in sleep disorders, atherosclerosis, cerebral and coronary vessels, convulsive states, severe heart disease, glaucoma, hyperthyroidism, liver disease. Do not take Teofedrin during pregnancy or breastfeeding, as well as in case of hypersensitivity to the components of the tool.
Features of the application Teofedrin
Teofedrin not be taken in the evening as it can be broken habitual sleep state. For the period of the drug is necessary to completely eliminate the use of alcohol.
Precautions should use the drug in the treatment of diabetes. Due to the activity of the drug in blood glucose increases blood chemistry. During the reception of the funds should be limited to the intellectual classes, work and driving vehicles.
Side effects Teofedrin aggravated by joint use of the drug with beta-blockers, indirect anticoagulants, fluoroquinolones, furosemide, cimetidine, carbamazepine, verapamil, antibiotics, hormonal contraceptives, MAO inhibitors.
Paracetamol is composed Teofedrin can cause intoxication when combined with inducers of liver enzymes and barbiturates. Ephedrine reduces the effectiveness of analgesics and tranquilizers. Bronchodilator effect is reduced by means of a one-time admission with beta-blockers.
Rifampicin reduces the concentration of theophylline in blood, oleandomycin, erythromycin, ciprofloxacin and raise it. Teofedrin reduce the therapeutic effect of doxycycline and its absorption. Using teofedrina treatment in combination with lincomycin unacceptable.
Avoid co-administration with Teofedrin antiepileptic and psychotropic drugs. Effect of antihypertensive agents, oral contraceptives and antidepressants when co-administered with Teofedrin usually decreases, and the effect of sleeping pills and diuretics can be increased.
Side effects Teofedrin
During treatment Teofedrin may cause epigastric pain, vomiting, nausea, tachycardia, tremor, insomnia, difficulty urinating.
In overdose possible Teofedrin nystagmus, ataxia, headache, weakness, heart disorder and low blood pressure, seizures, sweating, nervous excitement.
In case of overdose gastric lavage is shown. You also need to spend symptomatic therapy with constant monitoring of basic vital functions (respiration, pulse, blood pressure levels).
The drug Teofedrin should be stored in a place protected from light at a temperature from 15 to 25 ° C.