The active substance of Tegretol has a pronounced anticonvulsant and neurotropic action. In this connection, indications for use are Tegretol treatment of epilepsy and certain types of mental disorders.  Tegretol 400 mg

Pharmacological action

The active substance of Tegretol has antiepileptic, psychotropic, antidiuretic (in patients with diabetes insipidus) and analgesic (neuralgia) effect.

Tegretol not only reduces the frequency of seizures in patients with epilepsy, but also reduces the severity of their irritability, anxiety, aggression.

In the opinion of Tegretol trigeminal neuralgia weaken the severity of pain after 8 hours, and 72 hours is almost completely suppresses it. When diabetes insipidus significantly reduces urine output and reduces the sense of thirst.

During alcohol withdrawal, this drug increases the seizure threshold, reducing the increased excitability of the nervous system, reduces the severity of the tremor.

Tegretol used for the treatment of affective disorders as antipsychotic and mood stabilizer.

It is quite slowly absorbed from the digestive tract. The maximum effect begins to appear within 12 hours of receiving the initial dose.

Form release Tegretol

Tegretol comes in the form of round flat white tablets, with one side of risk and engraving «G / K», and on the other - «CG». Each tablet contains in its composition 200 mg of active substance.

Inactive ingredients: colloidal anhydrous silica, sodium carboxymethyl cellulose, magnesium stearate and microcrystalline cellulose.

The carton contains 5 blisters of 10 tablets each.

According to its active substance analogues Tegretol is carbamazepine, finlepsin, Mazepin.

Indications for use Tegretol

According to the instructions Tegretol is used in the following cases:

  • Simple and complex seizures (without loss or loss of consciousness);
  • Generalized tonic-clonic seizures;
  • Various forms of mixed seizures;
  • Central diabetes insipidus;
  • Acute manic psychosis;
  • Alcohol withdrawal syndrome;
  • Trigeminal neuralgia (idiopathic or multiple sclerosis);
  • Diabetic neuropathy with severe pain;
  • Idiopathic neuralgia glossopharyngeal nerve.

Indications for use Tegretol is also the treatment of bipolar disorder as a maintenance therapy. Regular use of the drug can prevent the development of acute or weaken its clinical manifestations.


Application Instructions for Tegretol is contraindicated in the following cases:

  • Age child under 1 year;
  • Violations AV - conduction;
  • Suppression of bone marrow hematopoiesis or intermittent porphyria in history;
  • Hypersensitivity to any of the components that make up Tegretol.

With extreme caution Tegretol is indicated for:

  • Glaucoma;
  • BPH;
  • Hypothyroidism;
  • Leukopenia and thrombocytopenia;
  • In old age;
  • Renal, hepatic, or cardiac insufficiency.

According to the instructions Tegretol is not recommended to be used simultaneously with MAO inhibitors, intake should be discontinued for at least the past 15 days prior to the appointment Tegretol.  Tegretol 200 mg

Indications for use Tegretol during pregnancy should be carefully evaluated by the attending physician, because it can contribute to the emergence of various disorders in the fetus development. During breast-feeding is forbidden to use the drug.

Dosage regimen Tegretol

According to the instructions Tegretol can be administered in combination therapy and monotherapy. The drug is taken during or after a meal with a small amount of liquid.

Dose selection for epilepsy is performed individually. In adult patients, treatment usually begins with the appointment of 100 - 200 mg Tegretol one - two times a day. Then gradually increase the dose. The maximum dose of not more than 10 tablets per day.

Children under 4 years of drug administered is based on 20 to 60 mg per kg body weight of the child and increased every 48 hours for 20 - 60 mg until the optimal dose. Children older than 4 years initially appointed ½ tablet Tegretol a day. Weekly dose increases to 100 mg.

Glossopharyngeal neuralgia, or trigeminal nerve originally assigned to two tablets a day. Then the next day the dose is increased by 2 times. Once the pain is completely gone, Tegretol dosage was gradually reduced.

When diabetes insipidus and withdrawal syndrome is usually administered one tablet to three times a day. In the opinion of Tegretol in the same dosage reliably relieves pain in diabetic neuropathy.

For maintenance therapy of bipolar affective disorders and acute edema manic psychosis use rather high dose - from 2 to 8 Tegretol tablets per day, divided into 3 doses.

Side effects of Tegretol

The drug can lead to quite severe side effects: dizziness, diplopia, headache, ataxia, oculomotor disturbances, nystagmus, orofacial dyskinesia, peripheral neuropathy, paresthesia, paralysis. Therefore, indications for use Tegretol should be carefully evaluated by physicians.

More often than not, in the opinion Tegretol causes patients drowsiness, fatigue, tremor, taste disturbance and disorder horeoatetoidnye.

The drug can cause a variety of mental disorders, manifested by disorientation, aggressive behavior, depression, auditory and visual hallucinations.

In the opinion of Tegretol often causes the development of atopic dermatitis, urticaria, erythroderma, increased sweating.

From the cardiovascular complications from taking Tegretol are: violation of intracardiac conduction, arrhythmia, increase or decrease in blood pressure, thrombophlebitis.

On the part of the gastrointestinal tract can be observed: dysgeusia, dry mouth, nausea, diarrhea or constipation, abdominal pain.

Often, reviews Tegretol is causing kidney damage that manifested an increase in body weight, the appearance of edema, urinary retention, urinary protein appearance, renal failure.

Other side effects of this drug include the development in patients of acute intermittent porphyria, folic acid deficiency, aplastic anemia, leukocytosis, sexual dysfunction, elevated intraocular pressure, agranulocytosis, pure red cell aplasia.

With an overdose of Tegretol likelihood of side effects and increase the power of their severity.

The drug should not be used in conjunction with many other drugs, because this can lead to increased toxic effects Tegretol.

storage conditions

Tegretol belongs to the list of drugs B. Shelf life - 3 years.