Tebantin - antiepileptic drug.
Pharmacological action Tebantin
The active ingredients of the drug are involved in the modulation of potassium channel action that promotes the release of neurotransmitters. Such processes allow to obtain stable analgesic effect. Tebantin maximum concentration in plasma is reached within three hours after a single dose of the drug. Repeated receptions achieve maximum concentration in blood decreases by about one hour compared to a single application. With prolonged use Tebantin stage of saturation is reached after one to two days from the beginning of his administration and lasts throughout the course of treatment.
After oral administration, active ingredients not associated with blood proteins, quickly penetrate the blood-brain barrier.
The preparation and analogues derived Tebantin body through the kidneys.
The instructions to Tebantin said that the drug is prescribed for epilepsy in adults and children over twelve years with the aim of therapy (monotherapy or combination therapy) for the treatment of epileptic seizures. In addition, a review of Tebantin noted that the drug has successfully established itself as a remedy for neuropathic pain.
At the moment, there are no experimental data Tebantin successful application as a component of combination therapy for the treatment of children under three years and for the purpose of monotherapy for the treatment of children under the age of twelve.
The drug is taken by mouth, with plenty of boiled water, regardless of the meal.
The preparation and analogues Tebantin designate adults and children over twelve years at a daily dose of 900-1200 mg. The initial dose of the drug is 300 mg three times a day, with the maximum interval at application Tebantin is not more than twelve hours.
The maximum daily dose - 2400 mg. Efficacy and safety of the use of higher doses to date has not been experimentally verified.
In a review of Tebantin it noted that in excess of the maximum daily dose of the drug could experience symptoms such as dizziness, blurred vision, diarrhea. In case of overdose it is recommended to wash out the stomach, and then take activated charcoal.
It is recommended to exercise caution while taking the drug and Tebantin analogues during pregnancy, as well as kidney failure. When using the drug in patients with diabetes need to control the level of glucose in the blood. In the case of acute pain in the abdomen, as well as symptoms such as nausea and vomiting, reception Tebantin should be stopped immediately.
During the period of treatment is necessary to give up driving, as well as work with complex mechanisms that require attention and concentration. When sleepiness, fatigue, dizziness, as well as the gain in body mass reception Tebantin should be discontinued.