Mifolian - a drug that is used for abortion (medical abortion).

Pharmacological action

The active ingredient is mifepristone Mifoliana, steroid hormone-like substances of artificial origin, is an antagonist of progesterone, a hormone produced by the adrenal glands active during pregnancy. Mifolian blocks the action of progesterone than causing disorders in the course of pregnancy, rejection and destruction of the uterus ovum.

Form release Mifoliana

It is produced in the form of tablets yellow in blisters containing 1 or 3 tablets.

Each tablet contains 200 mg of mifepristone Mifoliana and excipients (starch, lactose, magnesium stearate, sodium carboxymethyl starch, Valium).

The manufacturer of the drug Shanghai Hua Lian Pharmaceutical CO., LTD. (China).

Mifoliana analogues are the following drugs: Mirepriston, Mifegin, Mifepreks, Penkrofton, having in its composition the same active ingredient (mifepristin), but from another manufacturer.


Tablets Mifolian used to abort an unwanted pregnancy for up to 42 days after a missed period.

Also, the drug is used to induce labor in the presence of evidence, usually applies to them perenashivanie risk pregnancy.

Mifolian prescribed as a means of emergency post-coital contraception (ie, after the incident of unprotected intercourse), as well as for the treatment of uterine leiomyoma.

Instructions for use Mifoliana

According to the instructions Mifolian to terminate an unwanted pregnancy in early pregnancy are used as follows: three tablets at one time (of mifepristone 600 mg) in an hour and a half after a meal, drink water (100mg).

Pills Mifoliana occur strictly in the presence of a physician, and the next two hours after a patient spends in a specialized medical facility, equipped with everything necessary to stop uterine bleeding and other emergency services. To enhance the effect of the drug simultaneously with taking the drug Misoprostol, a synthetic prostaglandin, at a dosage of 400mg to stimulate uterine activity.

In the normal state of health of the patient to go home, warning about the symptoms that accompany the action of the drug. According to reviews Mifolian is pulling cramping pain in the abdomen, normally not too intense, weakness, dizziness, bleeding from the genital tract, increased body temperature to subfebrile figures - that is, the signs typical of spontaneous abortion.

Two days later the patient should undergo ultrasound of the uterus.

Within 14 days of receiving Mifoliana need to pass repeated ultrasound uterus and laboratory testing to determine the level of beta-human chorionic hormone. These measures are necessary in order to ensure that the pregnancy has been terminated.

In order to induce a generic process Mifolian instructions apply as follows: one tablet Mifoliana (200 mg) in the presence of a doctor inside. In the absence of the effect one day prescribe another pill intake. If labor has not followed, appoint agents, reducing the uterus (prostaglandins, oxytocin).

As a means of postcoital contraception drug is prescribed not later than three days (72 hours) after intercourse, 10 mg two hours before or two hours after a meal, one-time fee.

According to the instructions, in the treatment of uterine leiomyoma Mifolian take three months at 50 mg once daily.

Attention! Cautions

  • Mifolian strictly forbidden to use what else is a medical institution, it does not enter the free market is to prevent an independent application;
  • If the abortion has not occurred within 14 days after receipt, pregnancy should be interrupted instrumental way. Mifolian teratogenic, that is damaging the fruit. Save pregnancy after its application can not, because there is a direct risk of miscarriage, complications during childbirth, congenital anomalies and malformations of the fetus;
  • Take Mifolian as a regular postcoital contraceptive is strictly prohibited;
  • When taken during lactation, it is necessary to interrupt a period of two weeks;
  • Prohibited the simultaneous reception of the drug and non-steroidal anti-inflammatory drugs (paracetamol, aspirin, etc.)  Tablets Mifolian release 1 or 3 pieces. packaged

Side effects

Reviews Mifoliane from both patients and gynecologists, are evidence of its good tolerability. Side effects are rare, and we must distinguish between the expected effect of the drug as a medical abortion itself causes deterioration of health.

By the side effects are long Mifoliana bloody vaginal discharge, lohiometra (lochia delay in the uterus), uterine bleeding. You may receive the hives as a result of an allergic reaction to one of the components of the drug, as well as a feeling of discomfort, fatigue, dizziness, fainting, severe headache.

In a review of Mifoliane from doctors say long-term side effects: menstrual irregularities until amenorrhea, exacerbation of chronic inflammatory diseases of the genital tract atrophy of endometrium.

Contraindications Mifoliana

  • Adrenal, kidney, liver failure;
  • Uterine fibroids;
  • Diseases of the blood (anemia, porphyria, blood clotting);
  • Hypersensitivity to the drug;
  • Chronic gynecological pathology;
  • Diseases of the cardiovascular system;
  • Bronchial asthma;
  • Previous glucocorticosteroid therapy drugs;
  • Suspected ectopic pregnancy;
  • Pregnancy for more than 42 days after a missed period;
  • Pregnancy with contraceptive (hormonal and intrauterine);
  • In applying the drug to induce labor is not appointed in gestosis and other abnormalities in pregnancy (bleeding, abnormal fetal position, prematurity, prolonged pregnancy, etc.);
  • According to the instructions Mifolian as treatment is contraindicated in leiomyoma location tumor nodes in the submucosal layer, endometrial hyperplasia, a tumor size of more than 12 weeks of pregnancy;
  • Mifolian not prescribe smoking women over 35 years because of the high risk of complications of the cardiovascular system.

Storage regulations

Store in a dry place out of direct sunlight, at temperature not exceeding 25 ° C. Not for sale free!