Sustac (international name - Nitroglycerin) refers to a group of vasodilating agents to the active release of nitric oxide in the muscles of blood vessels. The drug has antispasmodic, relaxing and anti-anginal effect.
Structure and Composition
The main active substance - nitroglycerin 6, 4 mg.
Sustac discharged in aerosol form for internal use sublingual drops, concentrate for solution infusion solution for intramuscular injections and lozenges.
Pharmacological properties sustaka
Sustac activates guanylate cyclase leads to relaxation of smooth muscles of the heart muscles. The main active ingredients of the drug spasms of smooth muscle fibers of the heart, digestive tract, urinary tract, and bronchial tubes.
When administered solution sustaka expanding peripheral vein, blood flow is improved, therefore decrease the load on the heart, the pressure on the walls of the ventricular and lung normal oxygen supply.
Sustac promotes proper distribution of coronary flow stabilizes the sympathetic tone of the heart vessels and relieves pain.
In applying the drug may occur headaches and dizziness caused by the expansion of cerebral blood vessels. Frequent use of the drug may develop tolerance, so you should take breaks in reception for 10-20 hours.
When injecting a solution sustaka pill and therapeutic effect is achieved within 10-15 minutes and lasts for 3-5 hours.
Sustac appointed the following diseases:
- myocardial infarction;
- pulmonary edema;
- spasms of smooth muscles of the digestive tract;
- retinal artery occlusion;
- hypotension during surgery.
The drug can be administered as a prophylactic agent for circulatory disorders, to prevent the development of cardiovascular diseases.
Instructions for use sustaka
In accordance with the instructions Sustac in the form of tablets to be taken 2-4 times per day to 1 mg, sublingual dissolving tablet in the area. With strong spasm and acute attack of angina can take the drug every 30 minutes until the therapeutic effect.
Antianginal effects achieved after 2-3 minutes after administration, but no improvement in 30 minutes should seek medical treatment. The duration of therapeutic effect is about 2-3 hours.
For the prevention of angina Sustac should take 2 times a day before meals. In the initial stage of angina daily dose is 6 mg and at a severe stage - 15-20 mg. The maximum daily dose should not exceed 34 mg.
According to the instructions Sustac as a solution for internal use, and aerosols, 2-3 drops administered 2 times per day. The duration of the therapeutic effect is 2-3 hours.
Sustac as an ointment is applied in small quantities on the chest 2-3 times a day, rub lightly until completely absorbed.
Contraindications to receiving sustaka are hypersensitivity and intolerance to the components of the drug, intracranial hypertension, tachycardia, hemorrhagic stroke, severe stage of anemia, glaucoma, liver and kidney failure, pregnancy and lactation, children under 16 years.
Precautions The drug should be taken for violations of the gastrointestinal tract motility, cardiac tamponade, pericarditis, hypovolemia, hypotension.
Side effects sustaka
Sustac may cause the following side effects:
- the central nervous system - headache, dizziness, collapse, tremor, fainting, anxiety, convulsions, confusion, loss of coordination;
- of the cardiovascular system - a sharp drop in blood pressure, tachycardia, arrhythmia;
- on the part of the digestive system - nausea, vomiting, diarrhea, dyspepsia, dry mouth.
Chronic administration Sustac may cause allergic reactions - itching, hives, skin rash, angioedema, burning, dermatitis, eczema.