Supraks - a semisynthetic cephalosporin antibiotic for oral administration.  Supraks in granules

Pharmacological action Supraksa

Supraks - including the first antibiotic cephalosporin 3 generation, which can be taken orally. It is based on cefixime and possesses a broad spectrum of activity. The bactericidal mechanism of action of the drug sold by inhibiting the formation of the main component of cell walls of pathogens. Unlike previous generations Supraks their analogues resistant to beta-lactamases (enzymes, bacteria, that destroy the antibiotic, whereby its operation becomes ineffective).

According to the instructions Supraks depresses livelihoods gram (different streptococci) and Gram-negative (Haemophilus influenzae and E. coli, Klebsiella, Proteus, Salmonella, Shigella, serratsiya, tsitrobakter, gonorrhea) bacteria, but it resistant Pseudomonas aeruginosa, most species of Staphylococcus, Enterobacter and Listeria.

The bioavailability of the antibiotic is 40 - 50%, food intake did not reduce it (as with other oral cephalosporins), and only slightly elongates the time to reach maximum blood content. Among all the previous generations Supraksa analogues for oral administration, he has the most half-life because of this it can be taken one time a day, which is very convenient, for example, for young children.

Medicine Supraks well into the site of infection - in the middle ear cavity, paranasal sinuses, tonsils, lungs, biliary tract.

The urine excreted unaltered output 50% of the drug, whereby it proved highly effective in the treatment of urinary tract infections. About 10% of its output in the bile.

At the same time taking a diuretic drug excretion slows down in the blood for longer stays high concentration.

Supraks on responses had little dampening effect on the gut flora compared to its peers.

Product form

Supraks comes in two forms for oral administration - adults (400 mg capsule) and child (granules for suspension with a strawberry flavor 100 mg / 5 ml - 60 ml).

Indications Supraksa

According to the instructions the drug is intended to treat infections caused by organisms susceptible to cefixime. It tonsillopharyngitis, sinusitis, otitis media, acute and chronic bronchitis, pneumonia, urogenital infections (pyelonephritis, cystitis, uncomplicated gonorrheal urethritis and cervicitis). Good reviews Supraks got in pediatric practice.


Antibiotics should not be used in case of intolerance or allergic reactions to it, or other beta-lactam antibiotics (penicillins, cephalosporins and) during breast-feeding (at the time of treatment cease breastfeeding), children up to 6 months (no clinical trials).

With careful use of Supraksa possible with chronic renal insufficiency and in the elderly.

Instructions for use Supraksa

1 The drug is taken once a day inside. Before treatment, it is desirable to investigate the sensitivity of the pathogen to the antibiotic. Adults and children over 12 years Supraks 400 mg / day (1 capsule), the rate of an average of 7 - 10 days, it determines the physician. At impaired kidney function dose should be reduced.  Supraks capsules

For children the dose is calculated according to body weight - 8 mg / kg once per day or 4 mg / kg every 12 hours for 2 times per day. For them there is a special children's form - suspension with taste of fresh strawberries. 1 ml of the finished suspension contains 20 mg.

From 6 months to 1 year Supraksa daily dosage according to the instructions 2, 5 - 4ml, 2 to 4 years - 5 ml, 5 to 11 years - 6 - 10 ml.

To properly prepare a suspension, the pellets need to shake the vial, pour it in 2 stages with 40 ml of cold water each time carefully shaking until a homogeneous suspension. To the granules readily soluble, the suspension should be ready to stand up for a short time. Suspension Supraks not require refrigeration.

Before their counterparts Supraks has a significant advantage - it can be used to treat infections caused quite aggressive pathogens in the outpatient setting. Also, the drug supports sequential therapy, because of the seriousness of the disease when treatment begins with parenteral forms of cephalosporin for 3 generations, and after 2 - 3 days for the improvement of the patient can go to oral Supraksa.

Side effects Supraksa

In the opinion of Supraks during treatment can cause hives, itching, dry mouth, nausea, stomatitis, vomiting, diarrhea, abdominal pain, dizziness, headache. The blood may change the content of leukocytes and some biochemical parameters. Because of the severe consequences reception possible anaphylactic shock, pseudomembranous colitis, interstitial nephritis.