Stamlo - antianginal and antihypertensive from the group of calcium channel blockers of the third generation.  Stamlo 5 mg

Pharmacological action Stamlo

The main active ingredient of the drug - amlodipine. At the level of membrane amlodipine binds dihydropyridine receptors, thereby blocking the calcium channels. Calcium ions are required to reduce the muscle cells. Stamlo reduces transport of calcium ions into cells (primarily smooth muscle cells and cardiac muscle), thus decreasing their motility. The drug acts on the smooth muscle of blood vessels, dilates the coronary arteries (which feed the heart muscle) and peripheral arterial vessels measuring up to the arterioles (because they still have a wall of smooth muscle fibers). So Stamlo lowers total peripheral resistance of the vascular network, reduces preload on the heart and decreases myocardial oxygen demand.

During an attack of angina, coronary heart supply vessels constrict, the flow of oxygen to the myocardium decreases rapidly accumulating products of metabolism, which causes a characteristic pain in the heart. Stamlo dilates coronary arteries and, along with arterial blood increases the supply of oxygen to the heart.

Stamlo also prevents the compression of the coronary arteries (which happens for example when smoked). While taking medication People with angina, become better exercise capacity, slowing the progression of angina attacks and it is less concerned patients, allowing frequent use of nitroglycerine for the relief of it.

Against the background of long-term use may decrease Stamlo formed already left ventricular hypertrophy. In general, it has cardioprotective (protective) influence coronary heart disease.

The effect of receiving Stamlo gradual, it may take a few hours before the beginning of the action, that is, it is not the drug of first aid, but once the dose is enough for a day.

Reduced pressure Stamlo provides due to the effect on smooth muscle of the peripheral arteries, the hypotensive effect is dose-dependent. A single dose of the drug may reduce the pressure on the whole day, and it does not rise again, depending on the posture that takes people - standing or sitting. Pressure drops mild, so patients feel well during treatment and calmly tolerate ordinary physical activity. More Stamlo has a weak natriuretic effect - increases the excretion of sodium by the kidneys, which is also able to slightly reduce blood pressure.

Stamlo according to the instructions of complex interactions with other drugs while taking, so it is not suitable for treatment without a doctor.

Form release Stamlo

Stamlo release tablets 5 mg and 10 mg.


According to the instructions Stamlo shown in coronary heart disease (angina and vasospastic), and silent myocardial ischemia, high blood pressure, as an adjunct treatment for decompensation of chronic heart failure.

Contraindications Stamlo

 Stamlo 10 mg
 Do not use Stamlo with severe hypertension during pregnancy and lactation in case of intolerance of components. Carefully under constant medical supervision and instrumental in coronary heart disease on the background of reduced pressure in acute myocardial infarction, and for 1 month after, in chronic heart and liver failure, elderly, mitral stenosis, hypertrophic cardiomyopathy and sick sinus syndrome.

The efficacy and safety of Stamlo in children under 18 years are not known.

Instructions for use Stamlo

According to the instructions Stamlo taken orally 1 time a day. Begin with a dose of 5 mg / day, za1-2 week it was adjusted to 10 mg / day, this dose effectively prevents the occurrence of strokes. When vasospastic angina and once taking 5-10 mg. When hypertension the recommended dose of 2, 5 - 5 mg / day. In the treatment of chronic heart failure the initial dose of 2, 5 1 mg once a day if the patient tolerates it, then gradually increase the dose to 10 mg / day. The course can be prolonged, it determines the physician. In the case of completion of the course recommended a gradual reduction in dose.

side effects

Stamlo may have on the various systems of the body a number of undesirable effects, it may be, for example, headaches, drowsiness, seizures, mood changes, nausea, abdominal pain, palpitations and swelling, "tides" of blood to the face, dermatitis, dry skin, allergic reaction. If you notice such symptoms should stop medication and consult a physician.