Sotageksal (international name - sotalol) refers to a group of beta-blockers with antiarrhythmic activity. The drug reduces the heart rate and increases muscle tone of the bronchi.
Structure and Composition
The main active substance - 80 mg sotalol.
Auxiliary components: starch, cellulose, lactose, silica, magnesium stearate.
Sotageksal comes in tablet form for 80 -160 mg solution for injection in vials of 4 ml.
Pharmacological action Sotageksala
Sotageksal possesses antihypertensive and antiarrhythmic action. Preparation eliminates symptoms of coronary insufficiency and decreases intracellular levels Ca2 +.
As a result, major components Sotageksala decreases the excitability of the myocardium and normal heart rate. When the system is achieved by taking the drug hypotensive effect, normalizes blood pressure and blood flow in the walls of the atria. The positive effect of hypertension is achieved within 2 - 4 days after the start of dosing.
When receiving Sotageksala increased oxygen metabolism in tissues and eliminated factors causing the arrhythmia, including nervous irritability, high blood pressure in the vessel walls of the heart and circulatory disorders.
Good reviews Sotageksal got to be an effective drug for the treatment of complex diseases of the cardiovascular system in different stages of the tide.
Inderal, obzidan, Korgard and Inderal are analogues Sotageksala. These drugs have similar pharmacological properties.
Obzidan and Korgard besides antiarrhythmic action, hypotensive effect, control the operation of atrial cardiac muscle spasms.
Sotageksal prescribed for arrhythmia, ventricular tachyarrhythmias acute and chronic type of paroxysmal atrial fibrillation, supraventricular tachycardia type.
Positive feedback has Sotageksal as an effective antihypertensive drug.
Instructions for use Sotageksala
In accordance with the instruction Sotageksal as tablets should take two times a day to 80 mg.
The initial dose for hypertension is 80 mg, and further increases physician dosage to 160 mg per day.
Tachycardia Sotageksal assigned to 80 mg 2 times a day and after a week of receiving the dose increased to 160 mg two times a day.
The maximum daily dose should not exceed Sotageksala 480 mg.
According to the instructions Sotageksal as a solution for injection should be administered 2-3 times a day to 2 ml. The solution was administered for 5-7 minutes. After the start of treatment is necessary to control blood pressure, heart rate, the functioning of the digestive system and urinary tract.
Patients with hepatic or renal insufficiency is reduced dose 2 times. If you experience the first signs of allergic reactions reception Sotageksala should be lifted immediately.
Contraindication to Sotageksala are hypersensitivity and intolerance to the components of the drug, cardiogenic shock, cardiac failure, bradycardia, sinus type, angina, hypotension, myocardial infarction, cardiac hypertrophy, peripheral vascular disease of the brain, pregnancy and lactation.
With careful preparation is indicated for liver failure, metabolic disorders, psoriasis, depression in the elderly and children.
Side effects Sotageksala
Sotageksal may cause the following side effects:
- the central nervous system - headache, dizziness, drowsiness, fatigue, insomnia, anxiety dreams, confusion, impaired coordination, hallucinations, tremors;
- of the cardiovascular system - bradycardia, heart block cross, a sharp decline in blood pressure, vasospasm, Raynaud's syndrome, sudden angina, hypokalemia;
- on the part of the digestive system - vomiting, nausea, diarrhea, dyspepsia, flatulence, hepatic failure;
- The respiratory system - laryngitis, bronchitis, bronchospasm, rhinitis;
- on the part of the genitourinary system - decreased libido, irregular menstruation, painful ejaculation, decreased potency, dysfunction of the kidneys.
When receiving Sotageksala may appear allergic reactions - itching, hives, angioedema, alopecia, increased sweating, eczema, dermatitis, psoriasis.