Setegis - synthetic drug used in benign prostatic hyperplasia and hypertension.
Active substance Setegisa blocks alpha1-adrenoceptors cervical smooth muscle of the bladder and the triangle, the proximal portion of the prostate gland and urethra.
In benign prostatic hyperplasia Setegis helps to normalize urination, without impacting on the size of the prostate gland.
In addition, the active substance has Setegisa antihypertensive effect, lowers blood pressure and pre- and afterload on the heart and also reduces venous return to the heart.
Long term use of the drug, generally does not cause the development of reflex tachycardia.
The maximum therapeutic effect of the use of Setegisa reviews develops within 2-3 hours after ingestion. Duration - at least one day.
Setegis Tablets contain 1 mg (with the inscription "E451"), 2 mg (labeled "E452"), 5 mg (labeled "E453") and 10 mg (labeled "E454") of the active substance - terazosin.
Auxiliary components - ariavit Sunset yellow, magnesium stearate, povidone K-30, talc, lactose monohydrate, pregelatinized corn starch.
10 tablets in blister packs.
By analogues Setegisa containing the same active ingredient, terazosin include drugs, roots and terazosin-Teva.
According to the method of action to the closest analogues are medicines Setegisa Artezin, Doksaprostan, Zokson, doxazosin Cardura, prazosin, Urokard, Camiri, and Ebrantil pirroksan.
According to the instructions Setegis is indicated for use:
- For the treatment of hypertension;
- As symptomatic treatment of benign prostatic hyperplasia.
Setegis contraindicated for instructions apply:
- In childhood;
- If you are hypersensitive to terazosin or other alpha-blockers.
In pregnancy, as well as during lactation, Setegis should be taken with caution.
Setegis Review also prescribed with caution in:
- The cerebral circulation;
- Coronary heart disease, or other diseases of the heart;
- Insulin-dependent diabetes mellitus;
- Predisposition to orthostatic hypotension;
- Hypertensive retinopathy grade III or IV;
- The liver and kidneys.
Typically, tablets Setegis administered once daily (at night) at an initial dose of 1 mg.
The increase in dosage is recommended gradually, no more than once a week to avoid the development of arterial hypotension.
Maintenance dose in hypertension varies from 1 to 5 mg.
According to the instructions Setegis for benign prostatic hyperplasia is taken once a day for 5-10 mg, the maximum dose - 20 mg.
Efficiency Setegisa in benign prostatic hyperplasia can be assessed no earlier than a month or two of treatment.
The elderly, as well as in renal failure dose adjustment is not required Setegisa.
In overdose Setegisom and analogs can be observed:
For the treatment of the patient is recommended to symptomatic treatment and give a horizontal position with raised legs.
In an application with diuretics or other antihypertensive agents Setegisa dose should be reduced.
Side effects Setegisa
Setegis Review often leads to violations of the cardiovascular system. As a rule, after the first dose pills may develop hypotension, which is accompanied by vertigo, and in some cases - syncope.
Admission Setegisa in high doses can lead to reviews:
- Orthostatic hypotension;
- Muscle pain;
- Weight gain;
- Peripheral edema;
- Visual disturbances;
- Shortness of breath;
- Anaphylactic reactions;
- Nausea and vomiting;
- Edematous nasal mucosa.
Care must be taken while applying Setegisa with other antihypertensive drugs in order to avoid strengthening their actions.
Setegis refers to antihypertensive drug prescription. It should not be stored longer than 36 months pills.