Serdolekt - for the treatment of schizophrenia.  Serdolekt 12 mg

Pharmacological action

Serdolekt - a neuroleptic, which is derived phenylindole and provides antipsychotic effect.

The active ingredient of the drug - sertindole.

Positive feedback on Serdolekte associated with the fact that the drug, unlike other antipsychotic drugs, does not affect prolactin levels, no sedative effect.

Product form

Serdolekt release tablets.

Indications Serdolekta

The main purpose of the drug - treatment of schizophrenia.

Instructions Serdolekta: how to use

Time of taking the pills on time does not depend on food intake. Take Serdolekt once a day.

Treatment of schizophrenia using Serdolekta start with 4 mg dosage. Every 4-5 days, the dose may be increased until it reaches the level of 12-20 mg. In some cases, the destination may be 24 mg per day - this is the maximum allowable dosage.

Older patients before treatment is recommended to be screened to exclude cardiovascular pathologies. The dosage of these patients improve with care. The same approach is practiced to treat patients with moderate or mild hepatic impairment.

For patients diagnosed with renal insufficiency, the treatment regimen Serdolektom can not be changed.

If there was a break in treatment, and it lasted less than a week, continue therapy can last administered dose. If the break was over, the selection of dosage is carried out gradually, most often, by titration, and before the start of treatment necessarily carried out electrocardiography.  Serdolekt 16 mg

side effects

Serdolekt can cause shortness of breath, runny nose, nasal breathing difficulties, dizziness, seizures, various movement disorders, hypotension, edema, paroxysmal ventricular tachycardia and hyperglycemia (rare), hematuria, pyuria.

There are reviews of Serdolekte, cause weight gain, dry mouth, decrease in semen emitted.

In overdose sertindole observed tachycardia, slurred speech, drowsiness, transient increase QT interval. In this case, the drug overturned and washed stomach, give the patient a purgative and activated charcoal, if necessary, support breathing. Dialysis is considered ineffective antidote to the drug have not.

Contraindications Serdolekta

Serdolekt of instruction is contraindicated in severe cardiovascular disease, heart muscle hypertrophy, arrhythmia, congestive heart failure, bradycardia, acquired or congenital long interval QT, in case of hypersensitivity, severe hepatic insufficiency, during pregnancy or breast-feeding.

Children under 18 years do not prescribe medication. For emergency cases, when a patient with acute mental disorder began a nervous breakdown, Serdolekt not used.

Do not combine Serdolekt with drugs that provide anti-arrhythmic action relating to the IA or Class III - with dofetilide, amiodarone, sotalol, quinidine; with antipsychotic thioridazine; antibiotic erythromycin, gatifloxacin, clarithromycin; with antihistamines astemizole and terfenadine.

It is also contraindicated in combination with lithium Serdolekta with cisapride, cimetidine, ketoconazole, itraconazole, indinavir, Verapamil and diltiazem.