Retarpen (international name - Benzathine benzylpenicillin) refers to a group of antibiotics for the treatment of diseases caused by Treponema pallidum. The drug has a bactericidal and antibacterial action.

Structure and Composition

 Retarpen vial

The main active ingredient - benzathine benzylpenicillin.

Retarpen is available as a powder for solution intramuscular administration. 50 vials of 15 mL placed in a cardboard box.

Pharmacological action retarpen

Retarpen is a natural antibiotic that is created on the basis of mold fungus penicillin. On the pathogens and viruses drug bactericidal effect.

Basic substances retarpen destroy Gram negative microorganisms and gram-positive, such as Staphylococcus, Streptococcus pneumoniae, Bacillus anthracis, Neisseria gonorrhoeae, etc.

Positive feedback received retarpen as a drug with an effective anti-viral and anti-inflammatory action that destroys infections caused by Streptococcus and Treponema.

As a bactericidal antibiotic retarpen increases the effects of anticoagulants and increases the concentration of penicillin in the body.

Retarpen analogues having similar pharmacological properties, are Ampicillin, Amosin, Ospamoks, bitsilin and smallpox.

Amosin and smallpox as retarpen counterparts, have a wide range of actions. They kill Gram-positive and Gram-negative bacteria, as well as respiratory and skin infections.


Retarpen prescribed for the treatment:

  • diseases caused by Treponema pallidum, including syphilis, yaws, pint;
  • staphylococcal infections (enteritis, scarlet fever, endocarditis, sycosis, etc.);
  • infections caused by injuries and wounds of the skin;
  • tonsillitis.

Positive feedback received retarpen as a drug for the prevention of postoperative complications and attacks of rheumatic fever.

Instructions for use retarpen

Retarpen assigned to 1 injection of a solution into each buttock 1 time per day. If congenital syphilis children entered 1, 2 million. ED.

Adults in the early stages of syphilis in the course of 1 injection per day is administered solution of 2, 4 million. Units, and in the secondary stage - 2 times a day for 2 to 4 million. ED for 5-7 days.

In the period of treatment must constantly carry out diagnostic procedures and review clinical course of the disease in order to properly determine the dosage of the drug.

In the treatment of scarlet fever, tonsillitis and infectious wounds retarpen assigned to 0, 6 million. IU 1 time per day for 3-5 days. To prevent postoperative complications and seizures during articular rheumatism drug is administered by injection at 2 for 15 days.

When the first symptoms of allergic reactions the drug should be discontinued immediately.

Do not enter retarpen endolyumbalno and into the body cavity. At wrong introduction of the drug may be complications associated with impaired hearing and vision, locomotor activity.

Simultaneous reception retarpen and allopurinol increases risk of allergic reactions.

 Retarpen powder


Retarpen contraindicated in hypersensitivity and intolerance to the components of the drug, hay fever, epileptic syndrome, bronchial asthma.

Precautions drug is given during pregnancy and breastfeeding, children younger than 12 years.

Side effects retarpen

Retarpen can cause severe allergic reactions - urticaria, fever, angioedema, stomatitis, anemia, bronchospasm, leukopenia, dermatitis.

Chronic administration of the drug may develop resistance to it micro-organisms and fungi.