Propranolol - drugs used in cardiology.  Formula propranolol

Pharmacological action

Propranolol - this is a beta-blocker, which reduces the frequency and force of heart contractions, the emission values ​​of the heart, the need of the heart muscle of oxygen and its contractility.

The drug lowers blood pressure, increases the tone of the bronchi, strengthens the contraction of the uterus, reduces the severity of uterine bleeding occurring after surgery or childbirth.

Product form

Propranolol is produced in the form of tablets, capsules, solution.

Propranolol Analogs: Inderal, Inderal, obzidan, Propranobene.

Indications propranolol

The drug is used to treat angina, sinus tachycardia, hypertension, heart attack, atrial tachyarrhythmias, ventricular and supraventricular arrhythmia, supraventricular tachycardia, essential tremor; for the prevention of migraine attacks; to eliminate feelings of anxiety and symptoms of alcohol withdrawal.

There are good reviews about propranolol is used as an aid in thyrotoxic crisis, diffuse toxic goiter, pheochromocytoma. Analogs of propranolol can be used for the same indications, but the treatment regimen prescribed by the physician.

Instructions Propranolol: how to use

For the treatment of hypertension, taking into propranolol twice daily to 40 mg. If the pressure is lowered, the dosage is increased up to 120-160 mg per day. Permissible daily dose - 320 mg.

For the treatment of cardiac arrhythmias, angina take propranolol at a dose of 60 mg per day and then gradually move to 80-120 mg. Take the medication 2-3 times a day. Maximum dosage in this state - 240 mg.

For treating essential tremor and prophylaxis of migraine Propranolol administered in a dosage of 80-120 mg per day. By indications the dosage may be increased to 160 mg.

When paroxysmal arrhythmias and tireotoksicheskom Stroke should enter propranolol intravenously, slowly, at a dose of 1 mg. Two minutes later, the drug is administered again. If the result will not increase the dose up to 10 mg, but the control parameters of cardiac activity and pressure.

Women in childbirth to stimulate labor Propranolol according to the instructions introduced at half-hour intervals 4-6 times 20 mg. The dosage should be reduced if diagnosed in the fetus hypoxia.

To prevent complications after birth administered 60 mg daily for 3-5 days.

For patients with impaired liver function regimen is adjusted, and in violation of the kidney medicine can be taken in the usual manner.  Propranolol Tablets

side effects

Propranolol can cause weakness, depression, fatigue, insomnia, drowsiness, confusion, short memory loss, hallucinations, tremors, blurred vision, dry eye, increased heart rate, conduction disturbances infarction, arrhythmias, reduce the pressure, worsening of chronic heart failure, pain chest and epigastric pain, nausea, flatulence, diarrhea or constipation, change in taste, back pain, deterioration of potency or libido, arthralgia.

There are reviews of propranolol, indicating that the drug may cause fetal growth retardation, hypoglycemia and bradycardia in the fetus.

With an overdose of propranolol and analogues of the drug observed dizziness, bradycardia, severe reduction in pressure, AV block, blue hands or nails, heart failure, shortness of breath, can also start cramping, bronchospasm. To eliminate the effects of poisoning the patient do a gastric lavage, give activated charcoal, if necessary, atropine, lidocaine, cardiac glycosides, dobutamine, diazepam, glucagon, diuretics, establish a pacemaker.

Contraindications Propranolol

Propranolol for instructions contraindicated in acute heart failure, cardiogenic shock, sinus bradycardia, Prinzmetal angina, cardiomegaly, hypotension, asthma, diabetes with ketoacidosis, lactating women.

Under the supervision of children should take the drug, patients with chronic heart failure, hepatic insufficiency, Raynaud's syndrome, hyperthyroidism, depression, myasthenia gravis, psoriasis, pheochromocytoma, allergies, pregnancy, in the elderly.

Do not take propranolol at the same time with allergens and allergen extracts that are used in immunotherapy and for skin tests, as well as radio-opaque iodine-containing drugs.

Judging by the reviews of Propranolol, the hypotensive effect of the drug impaired nesteroidy, estrogens, steroids.

It is also considered that propranolol can affect the efficiency of insulin and of oral hypoglycemic drugs.