Prestarium - a drug used to treat hypertension
 Prestarium - a drug for the treatment of high blood pressure.

Pharmacological action

Prestarium reduces the pressure constricts arterial vessels, restores elasticity of the large arteries.

Patients with chronic cardiovascular insufficiency note that during treatment they restored the metabolic processes in the heart.

There are reviews of Prestarium confirming that it reduces afterload and preload on the heart, the pressure during the filling of the right and left ventricles, increases exercise tolerance, reduces heart rate.

Prolonged use Prestarium reduces the severity of left ventricular hypertrophy.

The hypotensive effect of the drug after taking an average starting dose of developing 4-6 h., And saved another day. After a month of application Prestarium pressure is stabilized, and there is such a state for a long time.

Withdrawal after cessation of treatment does not develop.

The active substance Prestarium - perindopril arginine.

Product form

Prestarium release tablets.

Analogs Prestarium - drugs Arentopres, Kovereks, Gipernik, Parnavel, Perineva.

Indications Prestarium

According to the instructions Prestarium prescribed for hypertension, chronic heart failure, stable ischemia.

Good reviews of Prestarium used to prevent re-occurrence of stroke in patients who have had previous stroke or transient suffering from circulatory disorders of the brain ischemic type. In this case, Prestarium administered with indapamide.

For these indications Prestarium analogues can be taken only after consultation with a cardiologist.

Instructions Prestarium: how to use

 Prestarium tablets
 Take Prestarium once a day, in the morning, before eating.

When hypertension patients in early treatment Prestarium administered in a dosage of 5 mg. If a month pressure becomes normal, the dose can be increased to 10 mg.

In order to prevent a sharp decline in pressure, three days before the start of treatment should stop taking the diuretic, if they were assigned. In the absence of such a possibility Prestarium begin therapy with a dosage of 2, 5 mg, monitor kidney function, potassium levels in the blood. If necessary, on the recommendation of a doctor, after a while the dose is increased.

Elderly patients are also administered 2 mg Prestarium 5, early treatment and dosage is gradually brought to 10 mg.

In heart failure, the drug often prescribed in conjunction with beta-blockers, digoxin. Permissible initial dose - 2, 5 mg. Up to 5 mg dose increased after 2 weeks.

If a patient suffering from heart failure, there is a tendency to develop hypotension during treatment to monitor renal function, pressure, content of potassium in the blood.

To prevent recurrent stroke in patients who have been diagnosed in the past cerebrovascular disease, Prestarium prescribed at a dose of 2, 5 mg. Take medication for two weeks, after which the patient is prescribed indapamide. According to the instructions Prestarium begin to take at any time after the first stroke, even after several years.

For the prevention of cardiovascular events in stable ischemic medication take two weeks to 5 mg per day. After two weeks, the dosage was increased to 10 mg.

Elderly patients taking 2 5 mg Prestarium for 7 days and then transferred to 5 mg, and in a week, during normal kidneys begin taking 10 mg once a day.

For patients with impaired renal function the treatment regimen is adjusted. In violation of the liver, judging by the reviews, Prestarium can be without consequences for the health to take the standard scheme.

Side effects Prestarium

Application Prestarium may cause worsening kidney function, acute renal failure, occurrence of cough, bronchospasm, rhinitis, eosinophilic pneumonia, respiratory problems, dry mouth, pancreatitis, cholestatic jaundice, nausea, diarrhea, abdominal pain, constipation, rash and itching on the skin, erythema multiforme, taste disturbances, poor appetite.

There are reviews of Prestarium confirming that the drug can cause confusion, fatigue, cramps, blurred vision, sleep, sexual dysfunction, dizziness, increased sweating, tinnitus, arrhythmia, heart attack or stroke, angina, a serious decline in pressure, worsening of mood .

In addition, during treatment Prestarium and analogues of the drug can occur neutropenia, thrombocytopenia, pancytopenia, agranulocytosis, hyperkalemia, elevated liver enzymes, leukopenia, decreased hemoglobin, hematocrit.


Prestarium for instructions contraindicated in galactosemia, glucose or galactose malabsorption, hypersensitivity to perindopril, ACE inhibitors during pregnancy, lactation, with a history of angioedema data.

Precautions Prestarium and analogues medications should take patients who due to hemodialysis, diuretics, salt-free diet compliance, or vomiting, diarrhea, decreased blood volume, as well as those who have diagnosed with angina, hyponatremia, a cerebrovascular pathology, bilateral stenosis of the arteries kidney, renovascular hypertension.

Under the supervision of patients taking Prestarium to 18 l., Patients with scleroderma, lupus erythematosus, hyperkalemia, aortic valve stenosis, obstructive hypertrophic cardiomyopathy, and those taking immunosuppressive drugs.