Polizhinaks - pharmacological combined antibacterial drug for vaginal use.
Structure and Composition
According to the instructions Polizhinaks comes in the form of vaginal capsules. This drug is a combination of neomycin and polymyxin B. Nystatin
In 1 capsule contains 35,000 IU Polizhinaks neomycin sulfate, 35,000 IU of polymyxin B sulfate and nystatin 100,000 IU. Besides the product contains adjuvants - tefoz 63, hydrogenated soybean oil, dimethicone 1000, gelatin, glycerol.
Externally Polygynax is oval soft capsules light yellow, which contain homogeneous watery mass. The internal contents of capsules tan.
Produced Polizhinaks 6 capsules in blister packs. The carton contains 1 or 2 blister agent.
Pharmacological action Polizhinaks
According to the instructions Polizhinaks has antibacterial, antifungal and bactericidal action. Nystatin has fungicidal activity (active against fungi of the genus Candida). Neomycin and polymyxin B act against many gram-positive and gram-negative microorganisms. It is noted that anaerobic streptococci and not sensitive to the drug.
In addition to these effects Polizhinaks even improves trophic (feeding) of the vaginal mucosa.
After introduction of the drug is evenly distributed along the walls of the vagina, and has bactericidal and fungicidal action. According to the instructions Polizhinaks practically not absorbed into the systemic circulation.
Polizhinaks recommended for treatment of the following infectious and inflammatory diseases:
- vaginitis (fungal, non-specific, mixed);
Also, this drug is used to prevent infection before gynecological interventions:
- diathermocoagulation cervical erosion;
- diagnostic curettage;
- before delivery.
This drug is contraindicated for use during the I trimester of pregnancy, and in case of hypersensitivity to the ingredients Polizhinaks.
Use during pregnancy and lactation
According to the instructions Polizhinaks can be used during the II and III trimester of pregnancy if the potential benefits of the drug greater than the risk to the fetus. During lactation is not recommended to use Polizhinaks. If there is a need for the appointment of the drug, the breast-feeding during treatment should be discontinued.
Dosing and Administration Polizhinaks
This product is intended for intravaginal administration. The capsule is injected deep into the vagina at bedtime supine (1 per day). From prevention to Polizhinaks administered for 6 days. In the treatment of vaginitis and vulvovaginitis course of therapy is 12 days. In the opinion of Polizhinaks it begins to exert a therapeutic effect after only 2-4 days from start of use.
If a woman has forgotten to enter Polizhinaks one or more times, it is recommended to resume use of the drug in normal dosage.
In the opinion of Polizhinaks rarely causes adverse reactions in the form of burning, itching, irritation. Very rarely allergic reactions (allergic eczema). Prolonged use may occur Polizhinaks adverse reactions that are typical of aminoglycosides.
In any case, in the event of alarm symptoms you should seek medical advice.
No reports of overdose of this drug.
Interaction with other drugs
According Polygynax instructions should not be used in conjunction with spermicidal agents, because they can reduce the activity of the drug.