Pipolfen dragees

Pipolfen - a drug used to relieve allergy symptoms.

Pharmacological action

Promethazine - the active substance medications has antihistamine activity, prevents the occurrence of itching and hives, often accompanied by allergic diseases, dries the mucous membranes of the mouth and nose.

Pipolfen also has antiemetic, sedative, hypnotic, antipsychotic effect.

The therapeutic effect pipolfen develops through 15-60 minutes. after receiving the pills or tablets; drug when administered intramuscularly - 20 minutes; IV - 3-5 minutes. Effect of the drug is stored for 7-12 hours.

Product form

Pipolphenum produced in the form of pills, tablets, solution for intramuscular, intravenous administration.

Indications pipolfen

Pipolfen of instruction prescribed for such allergic diseases: eczema, itching dermatosis, rash, serum sickness, exudative diathesis, angioedema, drug rash, anaphylactic shock, hay fever, insect bites, asthma.

Effective drug for the study of gastric secretion - reception pipolfen avoids complications due to the use of histamine as a stimulator of secretion.

When anesthesia medication used for sedation.

In neurology pipolfen prescribed for migraines and kinetosis syndrome (motion sickness), encephalitis, chorea and other diseases of the central nervous system, which are accompanied by increased vascular permeability.

In addition, pipolfen include comprehensive treatment of alcoholic delirium, psychosis, Meniere's syndrome, neurosis, trigeminal neuralgia.

In pediatric medicine prescribed for exudative diathesis in infants, asthmatic bronchitis, eczema, false croup, serum sickness, allergic dermatitis.

Instructions pipolfen: how to use

 Pipolfen solution

Administered intramuscularly to adults Pipolphenum 25 mg per day. According to the testimony of a drug can be administered more frequently - every 4-6 hours.

For the treatment of allergic diseases of drug administered in a dosage of 25 mg. Take it 1-2 times a day.

For the treatment, prevention of nausea and vomiting by Pipolphenum instructions administered in a dosage of 25 mg. This medication can be administered intramuscularly or taken orally.

For the treatment of kinetosis taking 50 mg per day in two doses. First time pipolfen take half an hour or an hour before the trip and once again - after 8-12 hours.

Acceptable daily dosage drug - 150 mg.

The surgery as a sedative in preparation for surgery pipolfen administered intramuscularly, is taken orally for the night - 25-50 mg.

In preparation for surgery in 2, 5 hours. The patient before it is introduced into the muscle of 50 mg means - together with lytic cocktail.

Children from 2 months to 6 years pipolfen administered 3-5 times per day, intramuscularly. Calculate the dose of drug by weight - 0 5-1 mg / kg. If the case is severe, your child can enter 1-2 mg / kg.

Children 6-14 liters. agent are administered in a dosage of 75-100 mg per day. Take it about 4 times per day.

Because pills and tablets pipolfen not divide children under 6 liters. recommended only intramuscular or intravenous administration of the drug.

Side effects

Pipolfen can cause drowsiness, anxiety, disorientation, blurred vision, increased frequency of seizures in children, tachycardia, reduced pressure, bradycardia, nausea, constipation, thrombocytopenia, agranulocytosis, leukopenia, skin rash, tinnitus, urticaria, photosensitivity, dermatitis, painful urination, increased sweating.


Pipolfen for instructions contraindicated in angle-closure glaucoma, sleep apnea syndrome (stopping breathing), alcohol poisoning or poisoning by opioid analgesics and opiates, coma, episodic vomiting in a child, the origin of which is unsettled.

Pregnant women, nursing women pipolfen contraindicated.

Children up to two months, the drug should not be administered intramuscularly or intravenously, and children up to 6 liters. - To give tablets or pills.

Also, do not prescribe pipolfen in case of hypersensitivity to promethazine, other derivatives of phenothiazine.

Precautions taken pipolfen elderly patients and those who suffer from respiratory diseases in the acute or chronic form, open angle glaucoma, disorders of the liver, bone marrow, kidney, cardiovascular disease, epilepsy, predisposition to urinary retention, Raynaud's syndrome, prostatic hypertrophy.

You can not take the medication simultaneously with MAO inhibitors and two weeks after receipt of the latter. It is also incompatible with the drug alcohol.