Phosphogliv - hepatoprotector with antiviral and immunomodulatory effects.
The drug is available
in the form of hard gelatin capsules for oral administration and for the preparation of a lyophilisate of a solution for intravenous administration.
The contents of capsules - a granular powder with a yellowish sheen and weak specific smell. Formulation 1 capsules: sodium glycyrrhizinate (35 mg), phospholipids (65 mg) and excipients (microcrystalline cellulose, calcium carbonate, calcium stearate, talc, colloidal silicon dioxide).
The lyophilizate composition comprises: phospholipids (500 mg), sodium glycyrrhizinate (200 g), and maltose.
Pharmacological action phosphogliv
Phosphogliv designed as an improved analogue of the drug used in clinical practice for the treatment of liver diseases. Part of the plant phosphogliv phosphatidylcholine derived from soybean seeds, restores the damaged membrane of hepatocytes - the liver cells, and glycyrrhizin acid, is the active component of licorice root, has found its application in the realization of the protective function of the drug.
With a wide spectrum of action, glycyrrhizic acid provides mixing phosphatidylcholine aqueous liquid in the gut and is used for the treatment of liver diseases of toxic and viral origin, including hepatitis B and C.
Glycyrrhizic acid and a part of phosphogliv salt contributes to the suppression of virus reproduction by stimulating the activity of interferon and of killer cells - the natural "defenders" of the body. Component phosphogliv and analogues of the drug has anti-allergic, anti-inflammatory, antioxidant and hepatoprotective effect due to its membrane stabilizing activity.
The combination of these components results in drug efficacy phosphogliv in medical practice.
Components of the drug after ingestion successfully absorbed from the gastrointestinal tract in the form of unsaturated fatty acids, glycyrrhetic acid, choline. These bioactive components hydrolysis well into the lungs, skin, liver and other organs.
Indications for phosphogliv are chronic liver disease (gepatozy different etiology, hepatitis), cirrhosis, liver poisoning, psoriasis, atopic dermatitis, eczema, radiation syndrome.
According to the instructions Phosphogliv not designed to receive during pregnancy, lactation, and in the presence of hypersensitivity to the drug. The caution is recommended to take Phosphogliv patients with portal hypertension.
Side effects phosphogliv
The feedback to the phosphogliv marked side effects such as dermatologic reactions such as skin rash, disappear after drug withdrawal. When using overdoses phosphogliv on indications currently observed.
According to the reviews phosphogliv breeding lyophilizate may not use glucose solution and saline.
appointed under the instruction to adults and children over 12 years. The capsules of the drug take 1-2 pieces 3-4 times a day during meals with some liquid. Duration of therapy in chronic liver disease is 6-12 months, with acute forms - 2-4 weeks.
Phosphogliv solution for injection is administered intravenously, two times a day for 10 ml for 10 days. By the end of therapy can be continued via phosphogliv capsules.
Preparations synonymous phosphogliv are Antral, Essentiale H Bitsiklol, Livolakt, Esau, Hepel N. To replace phosphogliv on analogue consult your doctor.