Phenibut - nootropic drug with anxiolytic activity.

Structure and Composition

The drug release  Packing Phenibut
 in the form of tablets. One tablet contains active substance - Phenibutum 250 mg.

The package of 10, 20 or 50 tablets.

Pharmacological action

According to the instruction is Phenibutum nootropic drug is gamma-amino-beta-fenimaslyanoy acid hydrochloride.

Application Phenibut has a direct effect on GABA-receptors, and has antiplatelet, tranquilizing, anti-oxidant and stimulating effect.

Phenibut effect on cerebral blood flow, normalizes tissue metabolism, which improves the functional state of the brain (linear and volumetric increases blood flow, reduces the tone of blood vessels of the brain, the brain has antiplatelet effects, improves microcirculation). In the opinion of Phenibut contributes to the disappearance or reduction of maximum anxiety, fear and anxiety, anticonvulsant action and has a positive effect on sleep.

The drug has no effect on the adrenergic and cholinergic receptors. Reduces the severity and duration of nystagmus, latency period lengthens. Phenibut positive psychological effect on the performance (memory, attention, accuracy and speed of the sensory-motor reactions). Reduces the symptoms of fatigue, improves mental performance, minimizes vasovegetative symptoms (headache, insomnia, emotional instability, irritability, a feeling of heaviness in the head).

Course application Phenibut improves mental and physical health, normalizes sleep, and improves memory. In the opinion of Phenibut significantly improves the condition of patients with speech and movement disorders. Patients asthenia feel improvement from the first day of the drug, increases the motivation to work. The drug has no excitation or sedation.

When such indications to Phenibut as neurogenic lesions of the stomach and heart, it stabilizes the process of lipid peroxidation. In elderly patients, it does not cause excessive lethargy and relaxing after-effect is absent. In the tissues of the eye improves microcirculation, reduces the inhibitory effect of ethanol on the CNS.

Phenibut - indications for use

According to the instructions Phenibut shown at:

  • anxiety and neurotic and asthenic conditions, fear, neurosis, increased anxiety, psychopathy, obsessive-compulsive disorder;
  • enuresis, tics, and stuttering in children;
  • insomnia and nightmares in the elderly;
  • urinary retention on a background of myelodysplasia;
  • primary open angle glaucoma (in combination with other drugs);
  • Meniere's disease, and dizziness caused by vestibular dysfunction of various etiologies (including traumatic and vascular disorders, otogennyh labyrinth);
  • alcohol treatment, for relief somatovegetativnyh and psychopathological disorders in withdrawal syndrome;
  • the treatment of delirium and predelirioznyh states in alcoholism (in combination therapy).

The indication for prevention of anxiety Phenibut is occurring prior to surgery or painful diagnostic tests, as well as the prevention of motion sickness when kinetosis.


Phenibut contraindicated in case of hypersensitivity to the active component.

carefully  Phenibut tablets
 It should be prescribed the drug for liver disease and erosive and ulcerative lesions of the gastrointestinal tract.

Dosing and dosing regimen Phenibut

According to the instructions Phenibut Inside, regardless of meals. The dosage, dosing frequency and duration of therapy depends on the tolerance, the patient's age and indications for Phenibut.

Typically, a single dosage for children ranges of 20-250 mg per day for adults - 20-750 mg per day.

Side effects Phenibut

In the opinion of Phenibut may cause the following side effects:

  • Digestive system: nausea, especially in the first receptions.
  • Central nervous system: agitation, increased irritability, drowsiness, headache, dizziness.
  • Allergy: itching skin rash.

Application Phenibut during pregnancy and breastfeeding

During pregnancy and lactation Phenibut can be used, but only if the ratio of benefits and risks for mother and child.

Drug interaction Phenibut

Phenibut enhances the effect of narcotic analgesics, hypnotics, antiparkinsonian, antipsychotic and antiepileptic drugs.


In the opinion of Phenibut affect the ability to drive and use other means that require high concentration of attention.

When expressed phenomena of motion sickness, such as severe dizziness and uncontrollable vomiting, the drug is ineffective.