Pariet - drugs used in gastroenterology, which has antiulcer and antisecretory activity.
The active ingredient of the drug is rabeprazole sodium. After absorption Pariet in gastric cavity is blocked enzyme provides for secretion from cells in the body cavity of hydrogen protons that disrupts the formation of hydrochloric acid. As analogs Pariet becomes effective after about 1 hour after administration and protects the stomach up to 48 hours. Maximum effect is observed in patients after 4 hours after drug administration. After the abolition of secretion is restored to its previous level for 2-3 days.
The above described steps, rabeprazole sodium detrimental effect on Helicobacter pylori - the bacterium that causes inflammation of the mucous layer of the stomach wall.
Pariet, reviews by clinical physicians, does not cause changes in metabolism, does not violate the cardiovascular, nervous, excretory system of the body, does not cause changes in the respiratory system, and is thus a fairly safe drug.
Release form of the drug and
Pariet available in tablets containing 10 and 20 mg of the active ingredient (rabeprazole sodium). The tablets are different colors - pink 10 mg, 20 mg - yellow, for 7 or 14sht in a blister, 2 blisters in the package.
The composition of each tablet, in addition rabeprazole sodium containing excipients: mannitol, magnesium oxide, low substituted hydroxypropylcellulose, magnesium stearate, ethylcellulose, hypromellose phthalate, diacetylated monoglyceride, titanium dioxide, red iron oxide, talc, ethanol, butanol, purified water, carnauba wax , F6.
Application of Pariet for instructions shown in the following states:
- The acute form, and acute gastric ulcer;
- Duodenal ulcer acute and in the acute stage;
- GERD (gastroesophageal reflux disease);
- Hypersecretion of hydrochloric acid (Zollinger-Ellison syndrome);
- Infection with Helicobacter pylori.
Instructions for use Pariet
The drug is prescribed 20 mg 1 time per day (1 tablet or 2 yellow pink). According to the instructions, it is desirable to take Pariet in the morning before a meal, although strictly necessary in terms of the impact of the drug it has not, but the discipline of the patient and allows you to more accurately adhere to treatment regimens. The tablet is swallowed whole without chewing, drinking plenty of water. The treatment of peptic ulcer disease is typically from 4 to 6 weeks. In most cases, after 4 weeks of application Pariet possible to achieve remission. If it does not, according to the instructions Pariet appoint additional courses for another 4 weeks.
- In gastroesophageal reflux disease:
Assign 1 tablet (20 mg of rabeprazole sodium) in the morning before eating. The course duration is 4 to 8 weeks. After elimination of the acute symptoms of the disease the dose is reduced to 10 mg per day, and this dose as a maintenance therapy is recommended for permanent use.
- Treatment batsillonositelstva Helicobacter pylori:
Therapy Pariet designed for 7 days, during which the drug is administered in a dosage of 2 tablets of 20 mg 2 times a day (morning and evening before the meal). To improve the efficiency of treatment in this case Pariet used in combination with other antibacterial agents.
Contraindications to the use of Pariet
- Hypersensitivity to the components of the drug;
- Do not take Pariet for pregnant women and nursing mothers, since there are no confirmed information about its complete safety during these periods;
- Infant and young child;
- The presence of a malignant disease of the gastrointestinal tract.
In accordance with the instructions, Pariet in combination with other drugs taken only on prescription, since their interaction can cause undesirable effects.
Side effects of the drug Pariet
There are medical reviews of Pariet, mentions the following side effects:
- Disorders of the different nature of the chair;
- The pain in the epigastric region;
- Nausea and vomiting;
- The drying of the mucous membranes of the mouth;
- Increased liver enzymes;
- Reduction of blood platelets;
- Skin rash on the type of hive, in rare cases, erythematous elements.
The specialists note that if you take Pariet for instructions, then the probability of occurrence of such side effects is very low. As a rule, these undesirable effects associated with individual intolerance to the components of the drug. All the side effects gets back development after stopping this drug.
Negative reviews of Pariet, wherever mentioned overdose are not available. There are cases of mistaken application of the drug at a dose of 80 mg. At the same time there was no evidence of violations of bodily functions, and the condition of the patients did not suffer much. However, an overdose of the drug should be avoided, trying to adhere strictly to the instructions, and the treating physician.
Pariet analogs are the following drugs: omeprazole, rabeprazole, Zulbeks, Hayrabezol and other preparations based on rabeprazole sodium. These and other analogs Pariet contain in their composition the same active ingredient, but differing in some of the excipients.
Conditions and terms
Store this medication out of the reach of children. The temperature should not be above 25
C, is not tolerated freezing or excessive heating. Shelf life Pariet packed - 2 years.