Capsules Oxybral
 Oxybral - a means to stimulate brain activity.

Pharmacological action

The active ingredient is Oxybral vincamine - one of the alkaloids plant periwinkle (Vinca minor). Vincamine improves metabolism in the brain tissues due to activation of the process of assimilation of glucose by brain cells. Normalized trophic tissues also due to stimulation of cerebral circulation - under the influence of Oxybral normalization of blood flow in the vessels of the brain, as it has a moderately selective dilatiruyuschee (expanding) effect on cerebral blood vessels pool. Numerous reviews Oksibrale from specialists suggest that the drug eliminates the oxygen deficiency of brain tissue by increasing the oxygen supply of neurons.

Thus Oxybral has complex effects on brain tissue, stimulating its function, improving energy delivery and removing brain tissue hypoxia.

It has no toxic effects on the blood, liver and kidneys.

Product form

Oxybral available in capsule form and as a solution for injection.

Sustained-release capsules, each containing microgranules two colors - blue and white.

The composition of one capsule: vincamine (30g) and auxiliary substances: sucrose, lactose, povidone, methacrylic acid copolymer, shellac, gelatin, talc, erythrosine, sepispers blue, indigo carmine. 20 capsules in blister.

The solution for injection is available in ampoules of 2ml, clear, colorless or slightly yellow. Each ampoule contains 15 mg of vincamine and Excipients: propylene glycol, tartaric acid, sodium metabisulfite, sodium bicarbonate, tartaric acid, purified water for injection. The package contains 5 vials.

Analogs Oxybral

An analogue of a drug Oxybral Vinoksin containing in its composition the same active ingredient, vincamine. Similarly, action the Aminalon, Cavinton and other stimulants neyrometabolicheskie. By the nature of the action exerted Oxybral analogs may also include Nootropil and other medicines, the active substance of which is piracetam. However, unlike Oxybral, piratsetamsoderzhaschie drugs do not have vasodilating action on the brain vessels.

Indications Oxybral

Application Oxybral shows for all kinds of violations or reduce brain activity. According to the instructions Oxybral appoint the following indications:

  • Drug rehabilitation after ischemic stroke and as a prevention with the threat of its development;
  • Cerebrovascular insufficiency;
  • Increased intracranial pressure;
  • Hypertension, especially with severe cerebral component;
  • Migraine and migraine attacks;
  • Attacks of vertigo of unknown origin;
  • Deterioration of concentration and memory due to various pathologies (atherosclerosis of brain vessels, the effects of traumatic brain injury, the effects of surgery on the brain, diabetic angiopathy of origin, etc.);
  • In the combined therapy for menopausal changes in women;
  • The deterioration of speech, sight and hearing, and neurological vascular genesis;
  • In the combined therapy in the treatment of mental illness;
  • The decline of mental abilities of older people;
  • Underdevelopment of intellectual abilities in children and adolescents, including severe mental retardation.

There are reviews Oksibrale confirming the feasibility of its use in cerebral palsy, as well as to stimulate the mental faculties, if necessary, intense mental activity.

side effects

When used in accordance with the instructions Oxybral well tolerated by patients. Side effects are rare and are caused, as a rule, individual hypersensitivity to Vincamine or exceeding the recommended dosage Oxybral. However, in medical practice marked following side effects resulting from administration of the drug:

  • Psychomotor agitation;
  • Irregular heartbeat;
  • headache;
  • Dizziness;
  • Dyspepsia: heartburn, nausea, dry mouth, blurred chair;
  • Allergic reactions: itching, rash, erythema, angioneurotic edema.

To eliminate the side effects reduce the dose of the drug or treatment is interrupted for 1-2 days. In the case of allergic reactions Oxybral replaced by another drug with similar effects.

Instructions for use Oxybral

 The drug Oxybral to stimulate brain activity
 Follow the instructions Oxybral 1 capsule (30 mg) 2 times a day. Also, the drug may be designated as an intramuscular or intravenous injection, in which case the dosage for adults: 2 ampoules intramuscularly or intravenously in combination with an isotonic solution for infusion twice per day.

Apply Oxybral in pediatric practice is recommended only as an intramuscular injection or intravenous infusion, single dose of 15 mg of active substance (1 USD), 1 or 2 times per day on prescription.

The duration of therapy with this drug is determined in each case individually. Because of its good tolerance and lack of pronounced toxic effect, when indicated possible long-term use - up to a year.

Oxybral prohibited to use without a doctor's prescription.


Application Oxybral contraindicated in the presence of individual hypersensitivity to any component of the drug, cardiac arrhythmias, brain tumors, hypokalemia, hypocalcemia, seizures undiagnosed origin. The drug is not recommended during pregnancy and breastfeeding because studies confirming its safety during these periods were not carried out.

In the case of treatment of opportunistic diseases other drugs at the time of application Oxybral need to notify your doctor about it as possible undesirable interactions.

Storage regulations

This drug should be stored in a dark, dry place at a temperature not exceeding 30 ° C. Shelf life 3 years. Keep away from children.