Osarbon (international nonproprietary name - atsetarsol) - antimicrobial and disinfectant agent used in gynecological practice (read: especially the female half of the population). Osarbon can be called one of the "last of the Mohicans" because in modern medicine use of arsenic compounds (which is the atsetarsol) is minimized. But this fact should not cause concern consumers - Osarbon rightly occupies its narrow therapeutic niche in modern gynecology, and is still popular.
Osarbon has only one dosage form and is available in the form of vaginal suppositories. One suppository contains 250 mg atsetarsola and several auxiliary substances: dextrose, boric acid, and Witepsol (a special role of glucose will be discussed below). Candles may have a slightly different color from white to cream or white with a yellowish tinge. Therefore, if you bought a candle differ in color from the previously acquired, it does not mean that the drug does not meet the quality or falsified.
The candles are packaged in blisters of 5 pieces, in the secondary packaging (carton) may be one or two of these blisters with instruction to Osarbonu for use.
Osarbon produced at the facilities of the Russian pharmaceutical plant "Nizhpharm" in Nizhny Novgorod.
Complete chemical analogue of the active substance Osarbona not. One can cite a few drugs having a therapeutic point of view similar to Osarbonom application. These include:
- Betadine (Hungary);
- Hexicon (Russian Federation);
- Makmiror (Italy);
- Fluomizin (Germany);
- Vagothyl (Poland).
There is, however, another drug, which includes atsetarsol. By the way, it is produced by the same of "Nizhpharm." This combined candle Osartsid whose composition, in addition to the aforementioned substances also include sulfanilamide.
The mechanism of action atsetarsola based on its ability to radically intervene in the metabolism of some protozoa (Trichomonas, amoeba, spirochetes) completely blocking their sulfhydryl enzymatic systems.
Many clinicians in their reviews about Osarbone emphasize the importance of maintaining an acidic environment in the vagina. Such conditions are necessary in order to avoid absorption and subsequent atsetarsola intoxication against its systemic action. With this purpose in the drug was administered glucose. The fact that glucose (sometimes instead of her candles dextrose added that, in fact, is equivalent replacement) - a beautiful "appetizing" substrate for the life of lactobacilli normal vaginal microflora. Recent and create the acidic "entourage" preventing resorption atsetarsola: they promote the process of breakdown of glucose, resulting in released lactic acid. Another ingredient Osarbona - boric acid - also serves to reduce the vaginal pH.
The instructions to Osarbonu is the only indication for the drug: Trichomonas colpitis. Patients should not confuse such specialization Osarbona since the disease is considered to be perhaps the most common form of inflammatory vaginal infections, sexually transmitted diseases. As the name implies, it colpitis caused by a pathogenic bacterium Trichomonas.
The only indication for Osarbona only shows that for other diseases have more effective drugs. But it Trichomonas colpitis can reasonably be called Osarbona fiefdom.
Brief guide to Osarbonu on application
Before applying Osarbon by appointment, you must give your body prone position, remove the spark plug from the blister and the most deeply inserted into the vagina. Multiplicity of reception - 1 suppository 1 time a day. Duration of treatment - 10 days.
Based on reviews Osarbone and results of studies conducted prior to registration of the drug, the following contraindications for its reception:
- excessive sensitivity to this drug;
- insufficient functioning of the kidneys and / or liver;
- hemorrhagic diathesis.
As the reviews Osarbone, the use of the drug does not result in a trail of unwanted side effects. Sometimes there are allergic reactions. Extremely rare - hepatitis, polyneuritis (total destruction of nerve fibers).
When using overdoses Osarbona in medical practice registered.
At the moment, research on the interaction Osarbona with other drugs have been conducted.
According to the instructions Osarbonu the drug sold in pharmacies by prescription, which is quite understandable, since atsetarsol (remember his arsenious nature) is poisonous.
Osarbon no effect on attention and reaction speed when driving vehicles and operating dangerous machinery.
Instructions for storage Osarbonu
Osarbon should be kept at a temperature no higher than 25? C in a place protected from direct sunlight.
Shelf life Osarbona is 3 years from the date of issue.