Ortanol belongs to the group of proton inhibitors and has an anti-ulcer effect. The drug blocks the secretion of hydrochloric acid and reduces its content in the digestive tract.
Structure and Composition
The main active substance - 20 mg omeprazole.
Auxiliary components: lactose, talc, polysorbate, povidone, giproloza, croscarmellose sodium, hypromellose phthalate.
Ortanol comes in packages, which capsules are placed in the 20-40 mg blisters.
The shell of each capsule contains potassium chloride, titanium dioxide, ethanol, iron oxide red and yellow, carrageenan, butanol, propylene glycol, ammonium hydroxide, purified water.
Pharmacological action Ortanola
Ortanol actively reduce acid production and acts as a prodrug which is activated in the secretory ducts acidic stomach environment and reduces the effect of H + K + ATP.
Appointed Ortanol heartburn for rapid inhibition of gastric secretion. The therapeutic effect of the drug is achieved within 2 hours, and lasts 24 hours. Ortanola Bioavailability is 40%, but in patients with chronic liver disease, it increases to 50%.
According to the instructions Ortanola main pharmacological effects are achieved in the course of treatment, which lasts for 4-5 days and tested 5-7 days after it.
The drug is metabolized in the liver and produces six metabolites which have little activity. Because the body Ortanol excreted by the kidneys and the bile.
Indications for Ortanola are gastric and duodenal ulcers, reflux esophagitis, secretion disorders and hypersecretory conditions (stress ulcer type adenomaz, mastocytosis, etc.).
Good reviews Ortanol received as a drug used in the treatment with the eradication of Helicobacter pylori (in patients with peptic ulcer disease).
Effective Ortanol heartburn, as well as for the prevention and treatment of injuries of the gastrointestinal mucosa caused by various inflammatory diseases.
Instructions for use Ortanola
In accordance with the instruction Ortanol necessary to take 20 mg, 1-2 times a day before meals. The drug can be dissolved in water or fruit juice.
At a stomach ulcer Ortanol be taken 1 time a day for 2-4 weeks, after which there should come a positive therapeutic effect. If it has not occurred, it is necessary to extend the treatment for two weeks.
In Helicobacter pylori eradication Ortanol assigned 2 times a day to 20 mg in combination with drugs of antibacterial action.
When hiatal hernia drug is given once a day 1, 20 mg for 3-4 weeks, and when complicated by a hernia course lasts 7-8 weeks.
Positive feedback has Ortanol as a drug for the treatment of excess acid secretion and restore balance in the digestive tract. In diseases such as Solling-Ellison syndrome and adenomaz, the drug should take 60 mg 1-2 times a day.
Contraindications to receiving Ortanola are intolerance and hypersensitivity to omeprazole and other components of the drug, age under 18 years, pregnancy and breastfeeding.
Precautions should be taken Ortanol patients with hepatic and renal insufficiency.
Side effects Ortanola
Side effects Ortanola mild and do not have a serious negative impact on the human body.
Side effects may include:
- On the part of the digestive system - vomiting, diarrhea, nausea, flatulence, anorexia and stomatitis. Patients with liver disease may develop hepatitis;
- Nervous system - headache, dizziness, impaired functioning taste buds, drowsiness. In rare cases - depression, aggression and loss of coordination.
- On the part of the musculoskeletal system - myalgia, muscle spasms, arthralgia.
After prolonged use Ortanola may appear allergic reactions - urticaria, angioedema, bronchoconstriction, itching and fever.