Oksamp - combined antibiotic belonging to the semisynthetic penicillins.
Structure and Composition
The drug is available in capsule form white. The contents of one capsule:
- active ingredients: 125 mg of oxacillin sodium, ampicillin trihydrate, 125 mg;
- Auxiliary components: sucrose, potato starch;
- Capsule: gelatin, acetic acid, titanium dioxide, propyl parahydroxybenzoate, methyl parahydroxybenzoate.
Oksamp - an antibiotic, combining the spectrum of action oxacillin and ampicillin.
Oxacillin - semisynthetic penitsillinazoustoychivy antibiotic belonging to the penicillin group. It has bactericidal properties against gram-positive microorganisms, such as: Bacillus anthracis, Streptococcus pneumoniae, Corynebacterium diphtheriae, Actinimyces spp., Streptococcus spp., Staphylococcus spp., Anaerobic sporeforming rods. Also acts on Gram-negative cocci and Actinomyces spp., Klebsiella pneumoniae, Haemophilus influenzae, Proteus mirabilis, Escherichia coli.
By the action of oxacillin resistant non-fermentative Gram-negative bacteria, Pseudomonas aeruginosa, and most strains of Morganella morganii, Providencia rettgeri, Proteus vulgaris.
Ampicillin - a semi-synthetic penicillin, bactericidal effect. Is active against gram-positive bacteria, which do not form penicillinase: Streptococcus pneumoniae, Streptococcus spp., Staphylococcus spp. It is also active against gram-negative organisms: Haemophilus influenzae, Neisseria meningitidis, Escherichia coli, Proteus mirabilis, Salmonella spp., Neisseria gonorrhoeae, Shigella spp.
According to the instructions Oksamp indicated for the treatment of diseases of infectious and inflammatory nature, caused by susceptible to malaria infections:
- otitis media, tonsillitis, sinusitis;
- pneumonia, bronchitis;
- infections of skin and soft tissue: impetigo, erysipelas, secondarily infected dermatoses;
- cholecystitis, cholangitis;
- cervicitis, gonorrhea, urethritis, cystitis, pyelitis, pyelonephritis;
Application instructions for Oksampa contraindicated in:
- lymphocytic leukemia;
- infectious mononucleosis;
- children aged up to three years;
- hypersensitivity to one or more of the ingredients.
Precautions should be prescribed according to the instructions Oksamp children whose mothers are sensitive to penicillin.
Application Oksampa during pregnancy and lactation
Appoint Oksamp during pregnancy should only be in the case of the balance of risks to the mother and fetus.
Oksamp passes into breast milk, it is recommended that in the case of its application to stop breastfeeding
Dosing and dosing Oksampa
According to the instructions Oksamp intended for ingestion.
Individual dosage of the drug are:
- Children from three to seven years - 100 mg / kg per day;
- children from seven to fourteen years - 50 mg / kg per day;
- children over fourteen years of age and adults - 0, 5-1 g / kg per day.
The daily dosage is divided into several stages. The duration of treatment ranged from five days to two weeks.
Side effects Oksampa
In the opinion of Oksamp may cause the following side effects:
- Gastrointestinal tract: nausea, vomiting, change in taste, goiter, diarrhea. There have been rare reviews Oksampe indicating the occurrence of pseudomembranous enterocolitis.
- Allergic reactions: eosinophilia, arthralgia, fever, angioedema, urticaria, conjunctivitis, rhinitis, flushing of the skin. In rare cases, anaphylactic shock may occur.
- The system of blood: anemia, neutropenia, leukopenia.
- Other side effects: superinfection.
Overdose Oksampom Review causes increased severity of side effects. In this case, gastric lavage, activated charcoal to accept and carry out the symptomatic treatment.
When long-term therapy for Oksampom instructions should regularly monitor the condition of the liver, kidney, and of the blood.
In the opinion of Oksamp can cause superinfection due to growth insensitive to the drug microflora. In case of superinfection should undertake appropriate changes antibacterial therapy.
Shelf life Oksampa
The drug is stored in a cool place at a temperature up to 20 ° C. Shelf life - 24 months.