Procainamide hydrochloride tablets
 Novokainamid - anti-arrhythmic drug.

Pharmacological action

Procainamide reduces the excitability of heart muscle suppresses biased sources of heart rate, has local anesthetic action.

Product form

Novokainamid release tablets, solution.

Indications novokainamid

Novokainamid of instructions used for ventricular tachycardia and arrhythmia, atrial tachycardia, ventricular arrhythmias, atrial fibrillation and flutter.

Instructions for use novokainamid

To remove the arrhythmia drug is administered intravenously. For this solution 100mg procainamide diluted solution of sodium chloride or dextrose, administered at a rate not greater than 50 mg / min. If necessary, the same dosage is administered every five minutes before the onset of the therapeutic effect or to achieve a dosage of 1g.

After elimination of the arrhythmia to maintain the resulting effect can enter the drug intramuscularly - 0 5-1gr, although preference in this case is better to give a tablet form of the drug, or to re-enter the solution intravenously.

If ventricular arrhythmia novokainamid taken orally, first in dosage 0, 25-0, 5-1gr and then to 0, 25-0, 5g per 4-6ch.

To stop paroxysmal ventricular tachycardia is administered intravenously at a dose of 0, 2-0, 5g at a speed of 25-50mg / min. Effectively and the introduction of "shock" dose - 10-12mg / kg for 40-60min., Followed by maintenance infusion - 2-3mg / min. After the attack stopped, the patient is a supportive therapy - administered 0, 25-0, 5g per 4-6ch.

In atrial fibrillation, procainamide according to the instructions prescribed in "shock" dose of 1, 25g inside. If no improvement is observed, an hour should give the patient another 0, 75gr and after every two hours at 0 5-1gr to improve.

 Novokainamid solution
 Acceptable dosages when using novokainamid inside: daily - 4gr, single - 1g; agent when administered intramuscularly or intravenously: daily - 3g (30ml solution of 10%), single - 1g (10ml 10% solution).

side effects

Procainamide can cause depression, dizziness, hallucinations, myasthenia gravis, seizures, ataxia, headache, bitter taste in the mouth, leukopenia, agranulocytosis, anemia, impaired sense of taste, reduction in pressure, ventricular tachycardia, skin rashes.

Due to the prolonged use of procainamide may develop lupus.

When administered intravenously novokainamid necessary to monitor pressure and heart activity of the patient. Note that with the rapid introduction of the solution in a patient can begin collapse, intracardiac block, asystole.

If overdose observed oliguria, fainting, confusion, dizziness, drowsiness, heart palpitations, vomiting, appetite loss, nausea, diarrhea, collapse, asystole, ventricular tachycardia. For the treatment of an overdose the patient was washed stomach prescribe medications that acidifying the urine, hemodialysis. If observed marked reduction of pressure, administered phenylephrine, norepinephrine.


Do not use novokainamid with AV blockade 2-3st (except when using a pacemaker), with flickering or ventricular fibrillation, leukopenia, arrhythmias, which developed due to poisoning by cardiac glycosides.

Be wary appoint procainamide in infants, heart attack, asthma, chronic decompensated heart failure, ventricular tachycardia, during and after operations (including dentistry), and hypotension, atherosclerosis in the elderly.

The instructions novokainamid also stated that it enhances the effect of antihypertensive, cytotoxic, anti-arrhythmic, anticholinergic agents, muscle relaxants.

During pregnancy, the use of procainamide is impossible, since it can cause hypotension in the mother, and as a result, utero-placental insufficiency. Also contraindicated means children under 18L., Lactating women.

During treatment, the patient novokainamid recommended caution in the management of transport, employment activities that require speed of mental reactions, increased attention.