Nitroxoline - antibacterial drug.

Pharmacological action

Nitroxoline active against gram-negative, gram-positive bacteria: enterococci, hay bacillus, streptococcus, diphtheria and gonorrhea, Shigella, Salmonella, Klebsiella, staphylococci, enterobacteria; against Mycobacterium tuberculosis, vaginal trichomonas, fungi Candida, molds, dermatophytes, agents of some deep mycoses.

Product form

Nitroxoline release tablets.

Indications Nitroxoline

Nitroxoline of instruction prescribed for urinary tract infections: cystitis, urethritis, epididymitis, pyelonephritis, prostatitis, the infected cell carcinoma and prostate cancer.

Positive reviews about Nitroxoline prescribed for the prevention of infection after holding the urogenital tract and kidney operations or diagnostic procedures (cystoscopy, introduction of a catheter).

Instructions for use Nitroxoline

As explained in the manual indications Nitroxoline prescribed to take after a meal or during a meal.

Permitted dosage for adults - 0, 4d, which take four reception at 0, 1 g. The treatment lasts for two or three weeks. In some cases, the dosage is increased to 0, 15-0, 2r, which also receive four times per day. The maximum allowable dosage of products - 0, 8 g.

Acceptable daily dosage for children after 5 yrs. - 0, 2-0, 4d, which take four reception at 0, 05-0, 1p. For children up to five years, the dosage is 0, 2 g / day. Duration pediatric use - 2 or 3 weeks.

Nitroxoline indication of chronic urinary tract infection is prescribed to take two courses with a break of two weeks.

 Nitroxoline pills
 As a preventive measure to prevent infection after surgery on the urogenital tract or kidney is prescribed to take Nitroxoline at 0, 1 g of the four stages over two or three weeks.

side effects

There are reviews of Nitroxoline, called after the application of vomiting, appetite loss, disorders of the liver, nausea, skin rashes, itching, ataxia, paresthesia, headache, polyneuropathy, tachycardia.

In rare cases, after prolonged use Nitroxoline causes optic neuritis. Also, long-term therapy the drug may lead to myelopathy, peripheral neuritis.

Data on overdose are no funds.

Contraindications Nitroxoline

Nitroxoline of instruction is contraindicated in: renal disease, severe hepatic dysfunction, cataract, during lactation, pregnancy, neuritis, increased sensitivity to the drug and the rest of the drug from the quinoline series.

Can not be combined with antibiotic nitrofurans. When combined with its levorin and Nystatin should be aware that they reinforce the effect of the drug.