Neurodiclovit - NSAIDs in combination with B vitamins
Structure and Composition Neyrodiklovita
Neurodiclovit produce a modified-release capsules. The main components are the components of a single capsule:
Vitamin B12 (cyanocobalamin) - 250 g;
Vitamin B6 (pyridoxine hydrochloride) - 50 mg;
Vitamin B1 (thiamine hydrochloride) - 50 mg;
Diclofenac sodium - 50 mg.
Auxiliary components: talc, trietilatsetat copolymer of ethyl acrylate and methacrylic acid, povidone K25. Sell Neurodiclovit in blister packs of 10 capsules.
Pharmacological action Neyrodiklovita
According to the instructions Neurodiclovit is NSAID with a combination of B vitamins on the body Diclofenac has analgesic, anti-inflammatory, antipyretic and antiplatelet effect. Analgesic and anti-inflammatory effects of diclofenac in rheumatic diseases significantly helps to remove pain, swelling of joints, morning stiffness, all of which reduces the functional state of the joints. In the postoperative period, trauma diclofenac reduces inflammatory swelling and pain.
Vitamin B1 contained in Neurodiclovit during phosphorylation processes in the human body is converted into kokarboksilazu - coenzyme various enzymatic reactions. Thus, thiamine plays an important role in fat, protein and carbohydrate metabolism, has been actively involved in the processes of neural excitation in the synapses.
Vitamin B6 is needed for the body to complete the work of the peripheral and central nervous system. Without vitamin B12 can not process normal blood formation and maturation of red blood cells.
According to the instructions Neurodiclovit appoint the following diseases:
Degenerative and inflammatory diseases of the spine and joints (ankylosing spondylitis, spondylarthritis, rheumatoid and rheumatoid arthritis, chronic arthritis, osteoarthritis);
Pain in nature rheumatic inflammation (after surgery and trauma, dental procedures, gynecological diseases and inflammatory diseases of upper respiratory tract);
Acute gouty arthritis;
Neuralgia and neuritis (sciatica, lumbago, cervical syndrome);
Rheumatic soft tissue.
Application Neyrodiklovita contraindicated in the following cases:
Inflammatory bowel disease Nature;
Pregnancy and breast-feeding;
Active liver disease;
Erosive and ulcerative lesions of the gastrointestinal tract, are in the acute phase;
Progressive kidney disease and severe renal insufficiency;
Partial or complete combination of asthma, intolerance to aspirin and other NSAIDs and recurrent polyposis of the paranasal sinuses or the nasal mucosa;
Severe heart failure;
Hypersensitivity to the individual components Neyrodiklovita and other NSAIDs;
The period of coronary artery bypass grafting.
In the opinion of Neurodiclovit should be used with caution in:
Ulcerative colitis, gastric ulcer and 12 duodenal ulcer;
Chronic liver failure, hepatic porphyria;
Chronic heart failure;
Chronic renal failure;
Peripheral arterial disease;
Alcoholism, smoking and other addictions;
At the same time receiving antiplatelet agents, anticoagulants, corticosteroids, selective serotonin reuptake inhibitors;
Coronary heart disease.
Dosing and dosing regimen Neyrodiklovita
According to the instructions Neurodiclovit capsules should be taken orally during meals, drinking plenty of fluids. For adults, the dosage according to the instructions of Neyrodiklovita 1 capsule three times a day at the beginning of treatment and as a maintenance therapy - 1 capsule 1-2 times per day. The duration of treatment depends on the severity and nature of the disease.
In the opinion of Neurodiclovit can cause the following symptoms of overdose occur: bleeding from the gastrointestinal tract, vomiting, diarrhea, epigastric pain, lethargy, tinnitus, convulsions, increased blood pressure, coma, respiratory depression, acute renal failure.
In case of overdose Neyrodiklovitom recommended to make an emergency gastric lavage, activated charcoal and take hold symptomatic treatment.
Side effects Neyrodiklovita
In the opinion of Neurodiclovit may cause the following side effects:
Nervous system: dizziness, headache, depression, drowsiness, sleep disturbances, aseptic meningitis (in patients with SLE, and others.), General weakness, irritability, and feelings of fear, nightmares, convulsions, disorientation in space.
Allergy: allergic vasculitis, rapidly developing anaphylactic shock, anaphylactoid reactions, swelling of the tongue and lips.
Storage conditions Neyrodiklovita
Neurodiclovit prescription. Neurodiclovit Store out of the reach of children, at room temperature for no longer than three years.
During the application Neyrodiklovita recommended to regularly monitor the pattern of peripheral blood, kidney and liver function and to check the stool for blood.
To avoid the risk of unwanted side effects from the gastrointestinal tract, take Neurodiclovit Review should be at the recommended dosage shortest time. To the effect of receiving Neyrodiklovita achieved as quickly as possible, it should be taken half an hour before meals.