Nebido - the drug, which is a synthetic analogue of the male sex hormone testosterone that contains it in the form of ether undecanoate. The drug is used in pathological conditions associated with a deficiency of testosterone. And, of course - only the male half of the population.
Nebido is available in the form of an oily solution is, in fact, the vast majority of testosterone preparations, except for a few tablet form and absolutely exotic gel for external use Androgel. The carton is embedded only one vial containing 4 ml of a solution of testosterone undecanoate to a concentration of active substance of 250 mg / ml. Himself solution is clear and has a yellowish tint.
Manufacturer Nebido is highly respected, not only in Europe, a German "Bayer Schering Pharma".
Analogs of Nebido
Analogues of Nebido in the global pharmaceutical market there is quite a lot. However, in this chapter will be listed only those that can be legally purchased in Russian pharmacies. Why is legal? The fact that this group of drugs is still implemented and that is called, "under the floor" as a component of pharmacological sports "recharge". So this black market sports pharmacology drugs testosterone provides much wider than in the State Register of medicines of Russia. There also will be discussed only those Nebido analogues that can be purchased with a prescription from a pharmacy legitimately.
So, to peers Nebido include:
- Sustanon-250 (The Netherlands). It is a mixture of four testosterone esters;
- Omnadren-250 (Poland). It also contains four testosterone ester, but other than Sustanon;
- Already mentioned Androgel (Belgium);
- Testosterone propionate (Russia);
- Andriol (Holland). Unlike previous drugs, Andriol - is a complete analog Nebido by active ingredient (containing exactly the same air - testosterone undecanoate), produced not only the injection, and in tablet form.
Testosterone contained in Nebido is known, is the major sex hormones in male organism. The lion's share is secreted by the testicles (in other words, testicles), and quite a bit - the adrenal cortex. Without testosterone will not be formed (and then maintain) a male sexual characteristics, sexual function implemented correctly proceed various processes in the bones and bone marrow, muscle, skin, central nervous system. Testosterone deficiency results in male hypogonadism, manifested impotence, decreased libido, chronic fatigue, depression, osteoporosis, degeneration of secondary sex characteristics.
Testosterone receptors found in most organs and tissues, so the effect of Nebido in addition to the arc "hypothalamus-pituitary-testes" applies, inter alia, on the musculoskeletal system, and on the hematopoietic system, and the kidneys liver. Use Nebido helps to reduce body fat while increasing muscle mass and bone preservation, increase sexual desire, as well as, judging by the reviews of Nebido, remove the depression that often accompanies men with hypogonadism.
Instructions for Nebido gives the following indications for its use:
- Primary hypogonadism. Its cause is a malfunction or underdeveloped testes from infectious diseases, injuries, surgery, or radiation exposure;
- Secondary hypogonadism. The origins of this pathological state are at a high level - in the hypothalamic-pituitary dysfunction which indirectly affects the testicles.
Regulations on the use of Nebido
The instructions to Nebido is recommended injections is not more than 1 time in 2-3 months (for the first injection, this time period can be shortened). This is sufficient to maintain a therapeutic concentration of testosterone in the blood at the desired level.
As advised doctors in their reviews of Nebido should be to pay special attention to the fact that the drug is subject only intramuscular administration. Still, a solution - the oil. Moreover, it should be administered slowly, keeping an eye on the fact that there was no vascular embolism (in other words, not to get oil into the vessel and it is not blocked). The slow introduction of the drug helps to avoid rapid short-term reactions such as asthma and cough reflex.
As before treatment and during it very useful to measure the concentration of testosterone in the blood fractions. This will determine the initial dosage and frequency of administration as well as make the necessary adjustments in the course of therapy.
In children and adolescents do not use Nebido. In relation to this age group do not even conducted clinical trials. But in the elderly, according to reviews of Nebido, drug understandably finds its admirers: in this age of rapidly declining levels of endogenous testosterone, which significantly reduces the quality of life.
According to the reviews of Nebido, the drug has the following contraindications:
- testosteronozavisimoy presence of prostate cancer or breast cancer in men;
- high levels of calcium in the blood that often accompanies cancer;
- swelling of the liver;
- being female.
Side deystvyae Nebido
The media are often found pseudo lengthy discourse about the terrible side effects, accompanied by the reception of androgens. A certain bit of common sense in this. But absolutely the same thing can be said about any drug, and the banal side effects of aspirin in any way less than the instructions for Nebido.
What can be expected, taking Nebido? Here is a brief list of adverse effects that may accompany the intake of this drug:
- joint pain;
- acne, itching;
- reversible gynecomastia;
- pain in the testicles and breast cancer, prostate disease;
- weight gain due to the muscle tissue;
- increase sex drive, frequent erections;
- irritability and aggressiveness.
Prolonged use of Nebido in high (greater than therapeutic) doses can lead to inhibition of secretion of testosterone, reversible decrease in sperm reproduction, reduced testicle, fluid retention in the body.
Nebido is released from pharmacies only by prescription.
The use of this drug in the elderly is associated with the risk of proliferation of prostate tissue. Data on the direct effect of Nebido in the risk of prostate cancer is not, however, the fact that the drug increases the already existing tumor, there is no doubt. In this connection, when applying Nebido to regularly inspect the prostate gland.
Instructions for Nebido storage
Storage Nebido is carried out in normal circumstances, nothing extraordinary is not required, sufficient room temperature. Use the drug can be in 5 years from the date of gathering packaging conveyor.