Misoprostol - a synthetic drug used in the treatment of peptic ulcers, which were formed when taking non-steroidal anti-inflammatory drugs, as well as for medical termination of early pregnancy.
Active substance misoprostol, a synthetic prostaglandin analogue E1, has cytoprotective action which increases mucus in the stomach and increases the secretion of the mucous membrane. Drug begins to act for half an hour after admission, duration of effect lasts for three to six hours.
Also Misoprostol causes uterine contractions, the cervix extends, and in combination with mifepristone, is used to terminate early pregnancy.
The drug is released in the form of white round tablets Misoprostol containing 200 mg of active substance, 3, 4, or 100 pieces per pack.
According to the instructions Misoprostol is used to:
- Prevention of gastric ulcers, which is associated with the use of nonsteroidal anti-inflammatory drugs, as well as for the treatment of acute duodenal ulcer and stomach;
- For termination of pregnancy up to 42 days, while the use of mifepristone.
Misoprostol tablets are contraindicated to apply at:
- Cardiovascular diseases;
- Diseases that are associated with prostaglandin-dependent - glaucoma, asthma, and hypertension;
- Endocrinopathies and diseases of the endocrine system, including diabetes and adrenal dysfunction;
- Liver and kidney diseases;
- Gormonalnozavisimyh tumors;
- Intrauterine contraceptives;
- Suspected ectopic pregnancy.
During pregnancy and lactation is strictly contraindicated for use in patients.
Before misoprostol in women of childbearing age should be performed first serum pregnancy test, and throughout the course of treatment should use reliable methods of contraception.
In establishing pregnancy, misoprostol should be immediately discontinued.
Also, do not use the drug before the age of 18 years and in case of hypersensitivity to misoprostol.
According to the instructions Misoprostol used with caution in:
- The cerebral circulation;
- Coronary heart disease;
Instructions for use Misoprostol
Misoprostol instructions are inside. A single dose of 1-2 tablets of misoprostol, renal failure dose should be reduced by half.
Duration of misoprostol depends on the efficiency of treatment and indications.
For abortion pills Misoprostol 2 taken two days after mifepristone.
In the opinion of Misoprostol can cause bloating, abdominal pain, nausea and vomiting, and diarrhea or constipation. In some cases, the drug causes itching, angioedema and skin rash. Also Misoprostol reviews can cause abdominal pain, are associated with uterine contractions, asthenia, fatigue and weight change.
Abortion treatment can only be carried out in combination with mifepristone and under medical supervision in specialized hospitals, which have the ability to provide emergency surgical gynecological care.
During the first weeks after the administration of misoprostol should not take aspirin and other nonsteroidal anti-inflammatory drugs.
The drug prescription shelf life of misoprostol - 2 years.