Lutein - hormonal drug has a positive effect on the reproductive system of women.

Pharmacological action

Lutein is the active substance progesterone is a hormone of the corpus luteum of the ovary.

Progesterone helps to normalize the secretory endometrium lining of the uterus from the transition of proliferative phase, characterized by the processes of renewal and recovery after menstruation, in the secretory phase, which is a preparation of the uterus for implantation of the egg.

Also contained in the preparation in the case of progesterone lutein fertilization facilitate and accelerate the transition of the uterus in a state comfortable for the development of the fertilized ovum. The use of lutein can reduce the contractility and excitability of the muscles of the uterus, which prevents the increase of uterine tone and prevents miscarriage. As the reviews, lutein helps to increase urine output.

Step lutein is not limited only influence on the reproductive system, the drug is able to regulate glucose level in the blood plasma, increased body temperature, stimulate respiratory activity, increase the level of amino acids in the blood.

Lutein, reviews confirm the recommended doses does not have contraceptive properties.

Lutein can be used vaginally (in the vagina) or sublingual (under the tongue). After the drug has been introduced into the vagina, the maximum concentration in the blood can be expected within 6-7 hours, faster acting Lutein in the form of sublingual tablets - in 1-6 hours.

After vaginal application of progesterone half will be displayed in 13 hours, and after sublingual - twice as fast.

Indications Lutein

The preparation of lutein is expedient to apply in cases when there is an endogenous progesterone deficiency, namely when:

  • menstrual irregularities;
  • premenstrual syndrome;
  • bezovulyatsionnyh cycles;
  • dysmenorrhea;
  • functional uterine bleeding;
  • endometriosis of the uterus;
  • infertility, which is due to luteal insufficiency;
  • artificial insemination;
  • threatened or habitual abortion, which accompanies progesterone deficiency;
  • the need to correct hormonal levels in women who are premenopausal;
  • hormone replacement therapy.


Lutein intravaginal tablets are not assigned with hypersensitivity, cancer of the reproductive system and breast and lactation.

Lutein sublingual tablets, in addition to the above contraindications not apply when unexplained bleeding from the genital tract, the presence of residues in the uterus after a miscarriage, severe hepatic impairment, cholestatic jaundice, thromboembolic diseases.

Instructions for use of lutein

Before the start of the application of lutein is recommended to conduct a survey of breast and cervix-vaginal area, in order to exclude possible contraindications.

Dose, route and duration of use of lutein physician should determine, taking into account the clinical picture and the individual characteristics of the patient.

Lutein candles designed for intravaginal application, one candle corresponds to 50 mg of progesterone. The drug should be injected into the vagina as deeply as possible in order to facilitate this process it is recommended to moisten a little candle.

When premenstrual syndrome, violations of the cycle, painful menstruation in premenopausal lutein candles are usually inserted into the vagina by ½ or 1 pc. twice a day. Apply the medication should be within 10-12 days in the second phase (after ovulation) menstrual cycle. To obtain the desired therapeutic effect of treatment is recommended for 3-6 consecutive cycles in premenopausal - before menopause.

Twice a day for half-1pc. Lutein candles inserted into the vagina during hormone replacement therapy. Intermittent therapy involves the use of the preparation with 15 to 25 day cycle, as continuous therapy - once 2-3 days.

When dysfunctional bleeding from the birth canal lutein intravaginal tablets are administered for 5-7 days 1 pc. twice a day. Continue treatment for the next 2-3 cycles according to the scheme recommended for intermittent hormone replacement therapy.

 Lutein candles
 Continuous treatment drug for six months suggests endometriosis, wherein the twice daily administered in 1-2 lutein candles.

When bezovulyatsionnyh cycles and miscarriage used twice a day for 1-3 lutein tablets vaginally. When habitual miscarriage is recommended to start to introduce the drug into the vagina during the cycle of conception and allegedly continued until 18-20 weeks of pregnancy.

When artificial insemination 3-4 lutein candles administered twice a day. Duration of treatment - 77 days from the date of movement of the embryo, the completion of the drug involves a gradual reduction in dose.

Lutein sublingual tablets are intended for use by placing them under the tongue. The drug is in a form guide, it is generally recommended to use 1 tablet 3-4 times a day, one tablet corresponds to 50 mg of progesterone.

Apply lutein sublingual tablets for premenstrual syndrome and cycle disorders should be for 3-6 consecutive cycles. When broken circuits hormone replacement therapy drug is used the last two weeks of the 28-day cycle and under continuous schemes - every day.

Dysfunctional uterine bleeding is treated for 2-3 months by applying the drug to the 15 to 25 day cycle for the suggested scheme. When bezovulyatsionnyh cycles and miscarriage single dose is doubled (2 lutein sublingual tablets), and for artificial insemination - 2-3 tablets at a time.

side effects

Lutein, reviews confirm well tolerated by patients, only in rare cases were observed adverse effects.

In applying the drug it is likely the development of such reactions as:

  • fatigue, weakness, drowsiness, depression, dizziness, headache;
  • changes in body weight, irrational fear, memory impairment, poor concentration;
  • painful menstruation, prolonged absence of menstruation, intermenstrual bleeding, violations of the outflow of bile;
  • acne, redness of the skin, thrombosis, allergic reactions.

Lutein sublingual tablets may trigger bleeding gums and dry mouth.

Additional Information

According to the instructions, reviews, lutein does not lose its therapeutic properties if its storage is done in a dark and dry place at room temperature.