Lidaza - enzymatic preparations for external use.

Pharmacological action

The enzyme hyaluronidase, which constitutes the basis of the drug Lidaza isolated from the testes of cattle.

Application Lidaza due to this substance leads to a splitting of hyaluronic acid (which is a cementitious component of connective tissue), reducing its viscosity and increasing vascular, tissue permeability, reduce swelling, soften scars.

There are also reviews of Lidaza, that the drug prevents and reduces contractures.

Product form

Producing Lidaza powder for solution for injections.

Indications Lidaza

According to the instructions Lidaza appoint: to eliminate post-operative, trauma, burn scars, treatment of non-healing ulcers (including radial), stiffness of the joints, osteoarthritis, ankylosing spondylitis, chronic tenosynovitis, soft tissue hematoma, severe disc disease in the lumbar region.

Good reviews of Lidaza applied in the preparation for plastic surgery to remove scars on the skin, for the treatment of traumatic lesions of peripheral nerves, nerve plexus.

Application Lidaza practiced in hydrocephalus, heart attack, pulmonary tuberculosis, inflammation of the upper respiratory tract and bronchi, in treatment of rhinitis, arachnoiditis, rheumatoid arthritis.

In ophthalmology agent is used to treat keratitis (for corneal scars formed thinner).


The drug according to instructions Lidaza contraindicated in: infectious inflammation, recent hemorrhage Hypersensitivity, lactation, pregnancy, cancer.

Inhalation Lidaza contraindicated in pulmonary tuberculosis with severe respiratory failure, bleeding from the lungs, with hemoptysis, fresh hemorrhage in the vitreous body.

You can not assign Lidaza simultaneously estrogenosoderzhaschimi drugs. Children drug is not indicated because of the lack of data on safety administration.

Influence of speed on physical, psychomotor reactions were investigated.

During treatment, it should be noted that the drug improves the absorption of drugs that are administered subcutaneously or intramuscularly, enhances the effect of anesthetics.

Instructions for use Lidaza

For treatment practice subcutaneous and intramuscular injections Lidaza, inhalations, baths, electrophoresis Lidaza also means dripping into the conjunctiva or do retrobulbar (behind the eyeball) injection.

 Lidaza injections
 The drug is administered subcutaneously under the scars. For injection, the powder is diluted in an isotonic sodium chloride solution or a solution of novocaine - 1ml. For the healing of scars, contractures, with bruises, ankylosing spondiloartite is administered near the affected areas every day, or c / o the day. During the course of treatment is administered injections Lidaza 10/06/15.

For the treatment of traumatic plexitis, other lesions of the peripheral nerves drug is administered subcutaneously in a volume 64ED a day for 12-15 injection. If necessary, treatment can be repeated.

For the treatment of rheumatoid arthritis is prescribed electrophoresis Lidaza - adults take 64ED agent dissolved in 30 ml of distilled water, adding 4-5kap. hydrochloric acid solution. Electrophoresis Lidaza lasts 20-30min therapeutic course consists of 10-15 procedures.

For the treatment of inflammation in pulmonary tuberculosis designate Lidaza injections in combination with inhalation.

For inhalation powder was dissolved in 5 ml of isotonic sodium chloride solution. The multiplicity of procedures - 20-25 inhalations. Repeat the treatment - at 1, 5-2mes.

For the healing of the cornea without consequences for the formation of a thin scar when keratitis antibiotics or sulfonamides combined with Lidaza (the drug is dissolved in 20 ml of novocaine or isotonic p-ra sodium chloride).

When retinopathy Lidaza for instructions injected under the skin of the temple - 0, 5 ml of the drug (one vial of powder dissolved in 20 ml of p-ra sodium chloride or Novocaine). A total treatment accounts for about 10-15 shots Lidaza.

In applying means it should be considered that the solution can not be administered through a catheter administered drug cations.

side effects

There are reviews of Lidaza causing allergy (hives, rash, itching), fatigue, chills, increased sweating, dizziness, fever, headache.

Intramuscular injection can cause redness, swelling, hives, itching, pain, fever, injection site Lidaza.

After instillation of the eye, eye injections may be swelling, redness of the eyelids, the skin on the face, periorbital area, the sclera.

Prolonged use can cause Lidaza local irritating effect means.

Overdose means possible. Judging by the reviews of Lidaza, in this case, nausea, dizziness, tachycardia, chills, vomiting, drop in pressure, local swelling, rash erythematous character, urticaria. To resolve overdose Lidaza recommended to take antihistamines, epinephrine glucocorticoids.