Levamisole - worming and immunomodulatory drugs.
The active substance has antihelminthic levamisole and immunomodulatory effects.
As anthelminthics Levamisole Dekaris highly effective in ascariasis and exhibits less effective when necatoriasis, strongyloidiasis, trihostrongiloidoze, ankilostomidoze. Immunomodulatory drug Levamisole amplifies and normalizes cellular immunity, probably affecting macrophages and T-lymphocytes.
Levamisole Dekaris produced in the form:
- White flat tablets containing 150 mg of active substance 1 tablet in the package;
- Light orange flat tablets containing 50 mg of active substance, 2 tablets in the package.
Excipients - povidone, lactose monohydrate, magnesium stearate, corn starch, talc, sucrose, and dye sunset yellow (for Levamisole 50 mg tablets).
Indications for use of levamisole
Levamisole is used as an instruction for a sedative if:
Immunomodulatory drug Levamisole Dekaris used for:
- Rheumatoid arthritis;
- Chronic active hepatitis B;
- Reiter's disease;
- Persistent viral hepatitis;
- Infectious diseases, including recurrent infections that are caused by Varicella Zoster virus and Herpes Simplex Type 1 and 2;
- Crohn's disease;
- Malignant neoplasms of the colon, bronchus, mammary glands. In the opinion of Levamisole is effective after radiation, surgery or chemotherapy.
Levamisole is used also in the treatment of leukemia intervals cytostatic remission of Hodgkin's disease.
According to the instructions Levamisole is contraindicated in agranulocytosis caused by the drug in history, as well as increased sensitivity to levamisole.
Levamisole does not apply to children under 3 years old, as children do not prescribe Dekaris Levamisole 150 mg.
Use caution when Levamisole myelosuppression, liver disease, kidney disease, cerebrovascular disorders, and while the use of other drugs that affect hematopoiesis.
Instructions for use of levamisole
According to the instructions Levamisole taken as a sedative once in the evening, one tablet of 150 mg. Children also receive a single dose in the evening, calculated on the basis of body weight:
- 10-20 kg (3-6 years) - 25-50 mg;
- 20-30 kg (6-10 years) - 50-75 mg;
- 30-40 kg (10-14 years) - 75-100 mg.
If you want to receive levamisole can be repeated after one or two weeks.
Immunomodulatory drug Levamisole can be taken every two weeks one tablet of 50 mg three consecutive days or 150 mg once.
Levamisole is not advisable to be used simultaneously with ethanol because of the possibility of disulfiramopodobnyh reactions, while the use of warfarin with levamisole may develop bleeding.
Strictly controlled studies safety of adequate levamisole dekaris during pregnancy and lactation was conducted, whereby the use of the drug is not recommended in these periods without strict indications and medical monitoring.
In the opinion of Levamisole can cause sleep disorders, anorexia, nervousness, nausea, constipation, depression, vomiting, dermatitis, diarrhea, skin rash, stomatitis.
It is also possible violations of taste or smell, myalgia, weakness, fever, arthralgia.
Agranulocytosis, increased cholesterol, acute pancreatitis, and thrombocytopenia of reviews Levamisole is extremely rare.
During treatment levamisole instructions alcohol is not recommended.
Shelf life levamisole - 5 years, the drug is released at the doctor's prescription.