Korvitol - means for regulation of blood pressure.
Korvitol refers to a group of blockers beta1-adrenergic receptors, contains metoprolol tartrate.
Korvitolu not peculiar sympathomimetic activity, it has a membrane-stabilizing effect. Application Korvitol reduces the force of heart rate, reduces the transmission rate of pulses on the atrioventricular node. Also metoprolol reduces renin activity slightly increases smooth muscle tone.
Korvitol after the internal application is well absorbed in the gastrointestinal tract, its bioavailability is 50%.
The maximum concentration of the active substance through the means of reaching 1 5-2ch after ingestion.
The product is produced in tablets.
Korvitol according to the instructions indicated for the treatment of cardiovascular diseases: hypertension, ischemic heart disease (including prevention of reinfarction, treatment of acute myocardial), arrhythmias.
Effective use Korvitola warns migraine agents.
Korvitol for instructions contraindicated in lactase deficiency, malabsorption syndrome glucose-galactose, hypersensitivity, hypotension, bradycardia, heart failure progresses, a state of shock.
Do not use tool for patients with atrioventricular blockade, sinoatrial 2-3 degrees, the weak sinus syndrome.
It is also contraindicated in patients with Korvitol bronchospasm, metabolic acidosis, severe pathology of the peripheral circulation.
You can not assign Korvitol simultaneously with monoamine oxidase inhibitors (except MAO inhibitors group B), for children up to 16 liters., Patients with severe liver disease.
The caution exercised when administering Korvitol elderly patients during a strict diet, diabetes mellitus, with 1st degree atrioventricular blockade, myasthenia gravis, pheochromocytoma, stenokadiey Prinzmetala, depression, severe renal insufficiency, hepatic impairment, psoriasis, severe reactions of intolerance in the past.
During the application Korvitol should exercise extreme caution when driving a vehicle, management of other dangerous machinery.
Before the operation, patients receiving Korvitol should alert the anesthesiologist.
Instructions for use Korvitola
Take Korvitol only orally, after a meal, you can not crush the tablet (just divide into pieces if necessary), swallow it whole.
According to the instructions Korvitol hypertension and angina drink one or two p / day or 50 mg for one p / day - 100 mg. The daily dose is in some cases increased to 200 mg, taken in two steps. When you receive this dose in Korvitol keep blood pressure under control.
When arrhythmia drink at 100mg Korvitol one, two p / day.
Acute Myocardial prescribed 5mg intravenous metoprolol. If portability is a normal, every two minutes over the same dose administered metroprolola, bringing its total number to 15 mg (no more than 5 mg per administration). After 15min, if the negative reactions to the drug not, a single dose of 50 mg administered orally Korvitol. After over two days every 6 hours taking 50mg of the drug. If an intravenous injection of less than 15 mg, the first oral dose should be 25 mg.
When emergency treatment is over, take two 100mg Korvitol p / day. Is the treatment of acute heart attack in hospital, constantly checking the pressure level and ECG.
For prevention of migraines take 100 mg means one or two p / day.
Permissible daily dose - 400 mg.
Adjust the dose in elderly patients and patients with renal failure is not required, and patients with hepatic impairment, the dose of metoprolol is corrected. If there is a need for discontinuation of treatment, it is done, gradually reducing the dosage - to prevent the development of withdrawal syndrome.
Application Korvitol can cause orthostatic hypotension and arterial, cardiac arrhythmias, heart failure symptoms, false angina, edema, atrioventricular conduction disease, Raynaud's syndrome.
Patients with severe peripheral circulatory disorders may develop gangrene.
Also after Korvitol may develop leukopenia, rhinitis, thrombocytopenia, dyspnea, bronchospasm, headache, dizziness, emotional lability, paresthesia.
Because drug therapy may disrupt sleep, concentration, can appear depression, confusion, hallucinations, nightmares, nausea, epigastric pain, vomiting, dry mucous, stool disorders. It may also impair vision and hearing, experience tinnitus, conjunctivitis, dry eye mucous allergies.
In rare cases, after Korvitol were recorded hepatitis, convulsions, myalgia, arthritis, development or aggravation of diabetes mellitus, arthralgia, weight gain, changes in libido, worsening of potency.