Kombispazm - combined medication used to reduce or relieve pain of various origins.

Pharmacological action

Kombispazm has analgesic, antipyretic, antispasmodic, miotropnymi (reduces peripheral vascular resistance) and holinoliticheskimi (blocks the effects of the neurotransmitter involved in the transfer of excitation in the nervous system) properties.

The structure includes Kombispazm paracetamol and dicyclomine hydrochloride. The action is due to the ability of paracetamol Kombispazm influence the thermoregulatory centers and inhibit the synthesis of prostaglandins, are actively involved in allergic and inflammatory processes.

Through the use of dicyclomine Kombispazm helps eliminate spasms of smooth muscles of the digestive tract, cupping or eliminate pain provoked spasms, reduce bronchial secretions, stomach, salivary glands and sweat glands.

Indications Kombispazm

Apply Kombispazm guide recommends to reduce or relief:

  • headache;
  • toothache;
  • neuralgia;
  • muscle aches;
  • radiculitis and rheumatic pain;
  • renal colic;
  • menstrual pain.


According to the instructions, Kombispazm not indicated for: tachycardia, urinary tract obstruction, myasthenia (muscle fatigue), glaucoma, hypersensitivity to paracetamol or dicyclomine. Contraindications Kombispazm lactating women and children under 7 years. Pregnant women drug is given on the strict condition.

Be wary of Kombispazm be at an enlarged prostate, urination arrest, congestive heart failure, tachycardia, ulcerative colitis, intestinal obstruction, benign hyperbilirubinemia, the liver or kidneys.

Instructions for use Kombispazm

 Kombispazm pills
 Tablets Kombispazm intended for ingestion. Depending on the nature and intensity of pain adults and adolescents over 15 years, the drug may be taken 1 to 4 times per day.

The recommended single dose Kombispazm for adults - 1-2 tablets.

Children 13-15 years of drug prescribed 1 tablet 1 to 3 times a day. Children 7-13 years Kombispazm User is recommended to take ½ tablet 1-2 times a day.

The maximum daily dose for adults - 6 grams (12 tablets) for children - 150 mg / kg. The interval between doses Kombispazm must be at least 4 hours. If during the two-week use of the drug, or side effects appeared was reached therapeutic effect Kombispazm reception should be discontinued.

side effects

Adverse effects Kombispazm reviews and clinical studies include:

  • thirst, dry mouth, difficulty swallowing;
  • sensitivity to light, dilated pupils with loss of the ability to see objects clearly, increased intraocular pressure;
  • blood flow, bradycardia, constipation, difficulty urinating, confusion, fever;
  • agranulocytosis, neutropenia, leukopenia, thrombocytopenia;
  • dry skin, rash on the skin.

Reviews Kombispazm indicate cases enhance gastrointestinal digestive reflux (stomach acid from entering and gastric juices into the esophagus, causing heartburn) when using the drug. Also Kombispazm can reduce the physical and mental reactions required for operating machinery and driving.

Additional Information

Kombispazm be fit for use for 3 years, provided it is stored in a dark, dry place where the temperature corresponds to 15-25 0 FROM.