Kokarboksilazu - vitamin-enzyme is used for the regulation of energy metabolism and tissue.

Pharmacological action

Kokarboksilazu is a substance formed from vitamin B 1   as a result of transformation in the body.

Kokarboksilazu affects the operation of the body through active participation in the neuro-reflex reactions, the sugar and fat metabolism. Application kokarboksilazu improves metabolism, glucose uptake, normalize the functioning of the heart muscle.

Lack kokarboksilazu causes acidosis (increased acidity level of the blood), which leads to severe abnormalities of many organs and systems of the human body. Cocarboxylase pregnancy is typically assigned at toxicosis, since this condition indicates failure metabolism.

Indications kokarboksilazu

Kokarboksilazu manual recommends taking at:

  • acidosis, which were provoked by diseases associated with disorders of metabolic processes in the body;
  • cardiopulmonary or respiratory failure in newborns including;
  • coronary heart disease;
  • hepatic and renal failure;
  • chronic cardiovascular disease;
  • poisoning;
  • acute and chronic alcoholism;
  • drug intoxication;
  • pathological processes that are associated with disorders of carbohydrate metabolism;
  • diseases in the newborn caused by oxygen starvation.

Kokarboksilazu, reviews confirm effective for the above pathologies.


The drug is not indicated for hypersensitivity to kokarboksilazu.

Instructions for use kokarboksilazu

 Kokarboksilazu hydrochloride

Cocarboxylase produced in the form of a lyophilisate for intravenous and intramuscular administration.

Before use, the powder can be dissolved in water for injection. Kokarboksilazu, which usually involves the use of complex treatment in adults and in patients 8-18 years appoint 50-100 mg once a day intramuscularly. Duration of treatment - from 15 to 30 days. When a diabetic coma or other severe conditions possible re-use kokarboksilazu the same dose 1-2 hours.

Maintenance dose once daily administered in an amount of 50 mg. Children under three months kokarboksilazu instruction recommends administered once a day for 25 mg, for children 4 months to 7 years, the dose may be increased to 50 mg.

Apply kokarboksilazu during pregnancy should only be prescribed by a doctor.

Side effects

Kokarboksilazu reviews described as well tolerated, only in rare cases, possible allergic reactions.

Furthermore, when administered intramuscularly at the injection site kokarboksilazu may occur itching, redness, swelling.

Additional Information

Keep kokarboksilazu instruction recommends at a temperature not exceeding 5 0 Since, in this case, the drug will be fit for use for 2 years.