Ketorol pills
 Ketorol is an analgesic drug with anti-inflammatory and antipyretic activity.

Pharmacological action

The active substance is ketorol ketorolac, which inhibiting activity of the enzyme cyclooxygenase, contributes to the inhibition of the biosynthesis of prostaglandins, which are modulators of inflammation, pain sensitivity and thermoregulation.

Analgesic effect Ketorol injections can be seen in half an hour after administration and maximum effect - after 1-2 hours.

Ketorol therapeutic effect persists for 4-6 hours.


Assign User Ketorol recommends that moderately or severely expressed pain syndrome: muscle aches and back pain, pain in the joints injuries, strains, sprains, post-operative pain, neuralgia, cancer, radiculitis, toothache, migraine, burns and others.

Instructions for use Ketorol

Ketorol whose use is expedient only in acute pain syndrome, and not for the treatment of chronic pain, is available in tablet form and a solution for intramuscular injection.

Depending on the severity of pain Ketorol tablets may be assigned only once or repeatedly.

Momentary usually recommended to take 10 mg (Table 1)., And re - 10 mg but not more than 4 times per day. Take Ketorol pills for longer than 5 days is contraindicated.

 Ketorol injections
 The solution for injection should be administered by deep intramuscular injection method. Patients younger than 65 years Ketorol injections administered at a dose of 10-30 mg once or the same dose - every 4-6 hours, with the maximum daily dose should not exceed 90 mg. Patients over 65 years Ketorol injections made by the above procedure, with the only difference that the maximum single dose of 15 mg must comply, and the maximum daily - 60 mg. Ketorol injections may be used for no longer than 5 days.

In the transition from intramuscular to oral administration ketorol should be taken into account the total daily dose of the drug on the day of transition - 30 mg for patients older than 65 years - 60 mg for patients younger than 65 years - 90 mg.

side effects

Ketorol tablets and injections can provoke patients such undesirable reactions as:

  • diarrhea, stomach pain, vomiting, constipation, flatulence, stomatitis, nausea, heartburn;
  • low back pain, acute renal failure, urinary frequency, nephritis (kidney inflammation), decrease or increase the amount of urine;
  • bronchospasm, laryngeal edema, rhinitis;
  • headache, drowsiness, dizziness, hyperactivity, depression, tinnitus, hearing loss, blurred vision.
  • increased blood pressure, fainting, swelling of the lungs;
  • leukopenia (increased white blood cell count), eosinophilia (increase in eosinophils), anemia (decrease in the number of erythrocytes or hemoglobin);
  • rectal, nasal, bleeding from surgical wounds;
  • purpura, skin rash, urticaria, Lyell's syndrome (allergic dermatitis as a reaction to drugs), Stevens-Johnson syndrome (the appearance of bubbles on the skin and mucous membranes of various organs);
  •   itching, hives, changes in complexion, skin rash, edema of the eyelids, difficulty breathing, wheezing, chest heaviness;
  • weight gain, swelling of the feet, toes, ankles, legs, face, tongue, excessive sweating, fever;
  • pain or burning at the injection site Ketorol.

Contraindications Ketorol

According to the instructions, Ketorol not used to treat chronic pain. Do not use this ketorol at:

  • bronchospasm (narrowing of the bronchial tubes as a result of muscle contraction);
  • "Aspirin" asthma (asthma attacks associated with the intake of salicylates);
  • hypovolemia (reduced blood volume);
  • angioedema (swelling of the limited depth of the mucous membranes or subcutaneous tissue and skin);
  • dehydration (dehydration);
  • peptic ulcers (expression of the esophageal mucosa from exposure to gastric juices on one of its segments);
  • erosive and ulcerative lesions of the gastrointestinal tract in the acute phase;
  • anticoagulation (reduced blood clotting);
  • hemorrhagic diathesis (diseases of the blood, which have a tendency to increased bleeding);
  • hemorrhagic stroke (bleeding in the brain caused by the rupture of blood vessels);
  • hepatic or renal failure;
  • concomitantly with other anti-inflammatory non-steroidal drugs;
  • violation of hematopoiesis;
  • high risk of bleeding;
  • hypersensitivity to ketorolac or other NSAIDs.

Ketorol, the use of which must be agreed with the attending physician is not given to pregnant and lactating women as well as children and adolescents under 16 years.

Be wary of Ketorol manual recommends cholecystitis (gallbladder inflammation), hypertension, congestive heart failure, asthma, renal failure, sepsis (blood getting into the infectious agents), active hepatitis, polyps (outgrowths of tissue) of the mucous membrane of the nose and nasopharynx , systemic lupus erythematosus (a disease of the connective tissue).

Additional Information

Keep Ketorol instruction recommends in a dark place where the temperature does not rise above 25 0 C. Shelf life Ketorol tablets and solution for injection - 3 years.