Isotretinoin formula
 Isotretinoin - a synthetic drug, vitamin A derivative used to treat acne.

Pharmacological action

Isotretinoin - systemic effects of the drug, which has anti-acne, immunomodulatory, A-vitamin-like, anti-dermatoprotektivnym and antiseborrhoeic effect.

It is used to treat severe forms of acne, as well as other kinds of skin diseases. It reduces inflammatory reaction of skin glands, reducing production, normalizing the composition and making it easier to sebum. Strengthens regenerative processes in the skin.

Product form

Isotretinoin Rakkutan produced as opaque oval capsules containing a suspension with 10 mg and 20 mg of the active ingredient.

Indications Isotretinoin

Isotretinoin Rakkutan - highly effective drug prescribed only in severe cases of acne:

  • Nodullyarnoy;
  • Disfiguring;
  • Nodulocystic;
  • At the risk of scarring;
  • Not amenable to other forms of therapy.

Isotretinoin is also used for the treatment of congenital ichthyosis, purulent hidradenitis sup-, severe rosacea, xeroderma pigmentosum, and some chronic dermatoses.


Isotretinoin protipokazan at:

  • Installed or planned pregnancy and lactation;
  • Hypersensitivity to the active substance - isotretinoin;
  • Hypervitaminosis A;
  • The simultaneous use of antibiotics of the tetracycline group;
  • Severe liver or kidney disease;
  • Diseases of the rectum (for rectal application).

In the opinion of Isotretinoin is quite effective for the treatment of acne during the passage of the full course of treatment.

Isotretinoin is used with caution in:

  • Liver and kidney diseases;
  • Diabetes;
  • Obesity;
  • Chronic pancreatitis;
  • Alcoholism;
  • Cardiac decompensation.

Instructions for use Isotretinoin

 Capsules Isotretinoin Rakkutana taken with food, usually one time a day, a large dose can be divided into several stages.

The dose Isotretinoin is calculated. The first four weeks taken at 0, 1 mg per 1 kg of body weight per day. Later, the dose can be adjusted, but not more than 2 mg per 1 kg. Usually, a long course of treatment up to 16 weeks. If necessary, the course may be repeated, making a break for at least several months.

side effects

In the opinion of Isotretinoin can cause various dermatological disorders - skin rashes, dryness of mucous membranes, itching, dermatitis, cheilitis, sweating, palms and soles of the feet, nail dystrophy. The drug can affect the organs of sight, causing photophobia, conjunctivitis, decreased night vision and corneal opacity.

Other side effects, in the opinion of isotretinoin, are rare - nausea or colitis, thinning hair, seizures, pain in muscles and joints, and nosebleeds.

Isotretinoin has a strong embryotoxic and teratogenic effects. Therefore, during treatment should use a few reliable methods of contraception, as well as to the treatment of a series of tests for pregnancy.

During pregnancy and lactation the use of Isotretinoin Rakkutana contraindicated.

Keep in mind that long-term use of the drug may develop chronic hypervitaminosis A.

In the treatment should avoid direct sunlight and UV therapy.

storage conditions

Isotretinoin is available on medical prescription. Shelf life - 3 years.