Pharmacological action Irunine
Irunine is an antifungal drug that has a wide spectrum of action.
It is noted that this medicine - triazole derivative. The drug inhibits the synthesis of ergosterol in the fungal cell membrane. Active Irunine, opinions of experts confirm that, with respect to yeast Candida spp., And dermatophytes fungi.
Dosage form Irunine:
Application Irunine indicated for the treatment of:
- onychomycosis, which are caused by fungi and yeasts or dermatophytes;
- kardidomikozov, which are characterized by different kinds of lesions of the mucous membranes and skin, the list includes vulvovaginal candidiasis;
- tinea versicolor;
- systemic mycoses, given cryptococcosis, systemic aspergillosis, blastomycosis, histoplasmosis, paracoccidioidomycosis and sporotrichosis;
- fungal keratitis;
- visceral candidiasis.
The only serious contraindication to the use of Irunine is a hypersensitivity to the drug, everything else can be determined individually.
Instructions Irunine: methods of use
According to the instructions Irunine, use the drug, the dosage form is the capsule and tablet, you need to immediately after a meal, it is only possible because of its optimal absorption. The capsules should be swallowed whole, not crushed. The duration of treatment and the dose should be determined by the physician individually.
It should be noted that for patients with AIDS or people who have transplanted organs, may need to increase the dose in half due to their impaired immune system.
Admission Irunine, reviews patients confirm it, may be accompanied by a variety of side effects. Their greatest number possible of the digestive system, which is responsible for the use of the drug nausea, dyspepsia, constipation, abdominal pain. It is noted that possible anorexia, hepatitis, cholestatic jaundice and elevated liver enzymes. In rare cases, the application may be accompanied by Irunine liver toxicity.
Among other negative consequences of possible headaches, fatigue, dizziness, peripheral neuropathy, menstrual disorders, hypercreatininemia, staining of urine a darker color, hyperkalemia, edema, pulmonary edema, congestive heart failure.
Can show a variety of dermatological and allergic reactions.
By Irunine counterparts, which are similar to them in action include: Itrazol, itraconazole, and itraconazole-radiofarm, Itramikol, Mikonihol, Orungal, Orungamin, Orun, Rumikoz.
Conditions and terms
Instruction Irunine notes that it should not be stored for more than 2 years in a dark and dry place, temperature not exceeding 25