Inderal - a synthetic drug, it belongs to the group β - blockers, used to treat high blood pressure, disorders of the heart.

Pharmacological action

Action Inderal is to block and ß1 ß1 adrenoceptor. Inderal reduces the oxygen demand of the myocardium, contractility of the heart muscle, cardiac output. With the use of propranolol can reduce blood pressure, increase vascular resistance.

According to medical observations and reviews Anaprilin also has antiarrhythmic effect, increases the tone of the bronchi (the result of the blockade ß2- adrenergic receptors), enhances uterine contractions, bleeding reduces labor and the post-operative period.

If ingestion Anaprilin rapidly absorbed and excreted. Half-life of the drug takes place within 3-5 hours, and long-term use - 12 hours. Inderal 90% excreted by the kidneys as metabolites, intact remains around 1%.

Product form

According to the instructions Anaprilin release tablets and capsules.

Tablets produced by 0, 010 and 0, 040g, in packs of 100, 50, 10 pieces. The release ampoules solution 0, 25% (1 ml) and 0, 1% (5 + 1 mL).

Indications Inderal

Assign Anaprilin of indications:

  • angina;
  • various heart rhythm disorders that are associated with lesions of rheumatic heart (arrhythmia, tachycardia paroxysmal and sinus arrythmia, atrial tachyarrhythmia);
  • hypertonic disease;
  • pheochromocytoma (Inderal is used with alpha-blockers);
  • digitalis intoxication of drugs;
  • hyperthyroidism;
  • cardiac ischemia

Methods of Use Inderal

According to the testimony Anaprilin necessary doses appointed physician instructions Inderal shows the average recommended dosage.

 Inderal injection

Typically Anaprilin use by injection three or four p. 10 mg daily for up to a meal (15-30 minutes).

Possibly a gradual increase in the dose specified, if there is not sufficient effect. In this case Anaprilin yield the same three-four rows. per day, but 20-40mg (there are cases where the dose was increased to 200 mg per day).

When arrhythmia Anaprilin indicated for three or four p. a day for 0, 010-0, 030g.

During the first three days of angina give Anaprilin four p. at day 0, 020g, and the next 4, 5, 6 - three times daily at 0, and 0 040g, 020g fourth reception. From 7 days give 0, 040g Inderal four p. in a day. After continued use of propranolol for 0, 16 g per day or increase the daily dose of 0, 20-0, 24g.

With open-angle glaucoma to reduce intraocular pressure, prescribe 1% solution of Inderal.

Intravenous administration of propranolol practice to suppress angina attacks, heart rhythm disturbances.

In strict medical Anaprilin appoint and children. It is given three to four rows. a day, hoping to 0, 25-0, 50 mg per kilogram of body weight of the child.

Side effects after using Inderal

According to medical reviews, Anaprilin causes these side effects:

  • vomiting;
  • nausea;
  • diarrhea;
  • worsening of sleep;
  • dizziness;
  • general weakness;
  • hypotension;
  • Raynaud's syndrome;
  • itching of the skin;
  • bradycardia;
  • Symptoms of insufficient blood circulation;
  • impotence (with prolonged use);
  • bronchospasm.


Receiving instructions on Inderal is contraindicated in:

  • myocardial infarction in the acute stage;
  • bronchial asthma;
  • diabetes mellitus with ketoacidosis;
  • disorders of peripheral arterial blood flow;
  • spastic colitis;
  • sinus bradycardia;
  • hay fever;
  • complete and incomplete atrioventricular block (with left- and right heart failure);
  • propensity to bronchospasm.

Also, on the basis of medical advice and reviews, Anaprilin simultaneously with hypoglycemic agents prescribed only under strict medical supervision (to avoid hypoglycaemia).