Indapamide - diuretic.

Pharmacological action

Indapamide - sulfonylurea, used in the treatment of arterial hypertension. The drug causes a drop in pressure, not affecting the amount of urination.

The use of indapamide also decreases contraction of the vessel walls (by changing the permeability of cell membranes for calcium).

Reviews of indapamide suggest that after treatment of left ventricular hypertrophy is less pronounced, and its hypotensive effect is evident even in patients on hemodialysis.

This tool does not affect lipid metabolism, carbohydrate metabolism, including in patients suffering from diabetes mellitus.

Product form

Release indapamide tablets, capsules. Manufactures and indapamide retard - sustained-release tablets.


The only indication of indapamide is its participation in the treatment of arterial hypertension.

Instructions for use of indapamide

 Indapamide retard
 The drug is taken orally, 1, 25-1, 5 mg per day, usually in the morning.

Indapamide retard take 1, 5 mg, and one p / day.

As indicated in the instructions indapamide, if after a month, the two expected effect is observed, it is necessary to consider the application of other treatment regimens with other drugs. To increase the dose in this case is not advised, as it does not increase the hypotensive effect, but only a diuretic, which is inconsistent with the testimony of indapamide. Moreover, the application of high doses can lead to side effects.

Side effects

Indapamide may cause paresthesia, muscle pain, weakness, headache, vertigo, fatigue, thrombocytopenia, agranulocytosis, aplastic anemia, hemolytic, cardiac arrhythmia, hypotension.

There are reviews of indapamide, that its application has led to the development of negative reactions on the part of the digestive system (constipation, nausea, pancreatitis, dry mouth, impaired hepatic function), the immune system (allergic reactions), respiratory system (pharyngitis, cough, sinusitis ).

Patients with hepatic insufficiency may develop hepatic encephalopathy after treatment.

Contraindications to the use of indapamide

Indapamide for instructions contraindicated in patients with severe impaired hepatic function, renal failure, drug intolerance, circulatory disorders of the brain, hypokalaemia, gout.

Concomitant use of indapamide with medications, increase the interval QT (for example, with cisapride).

Do not use the drug for pregnant women, lactating women, children up to 18L.